Xiaoyu Zeng|曾笑雨

Excited to share our latest work in @nature.com showing shared neural substrates for parenting and prosocial helping behavior. Full text available here: rdcu.be/e6PnY

Aperiodic 1/f noise drives ripple activity in humans - Nature Communications How aperiodic 1/f noise drives ripple activity in human brain and impacts on ripple detections is not fully understood. Here authors show that ripple detections should be driven by the 1/f noise, whic...

Ripple oscillations are central for memory and sleep.

But ripple detection in humans remains challenging. Here we introduce a simulation approach in @natcomms.nature.com as common ripple detectors mainly pick up 1/f noise and not genuine oscillations

👇
www.nature.com/articles/s41...

#neuroskyence

Conjunctive population coding integrates sensory evidence to guide adaptive human behavior. New work led by @jonasterlau.bsky.social in @pnas.org. We used human intracranial EEG to understand how coordinated population activity supports context-dependent behavior. www.pnas.org/doi/10.1073/.... (1/4)

Rethinking the centrality of brain areas in understanding functional organization Nature Neuroscience - Parcellation of the cortex into functionally modular brain areas is foundational to neuroscience. Here, Hayden, Heilbronner and Yoo question the central status of brain areas...

New Perspective from myself, Sarah Heilbronner and @myoo.bsky.social . “Rethinking the centrality of brain areas in understanding functional organization” in Nature Neuroscience. 🧵

rdcu.be/eVZ1A

A real-time, closed-loop framework using human intracranial recordings during value-based decision-making. 🧠Respect for the staggering amount of time and effort @julienbastin.bsky.social and his team must have invested to make this happen.
#ieeg
www.researchsquare.com/article/rs-8...

I think almost all scientific projects should be planned carefully. And I think an app can dramatically improve that. So I wrote an app for that (free for now, if you can fund this let me know). I tested it quite a bit (>8000 users in beta so far). try it: planyourscience.com

First ever public presentation of single cell evidence for non-spatial grid cells by Elena Gutierrez, Seb Veselic from Steve Kennerley lab. Steve an I have been dreaming of this moment for nearly 10 years. #sfn25

Choosing the best or avoiding the worst: complementary and opponent value signals in the human brain Whether the brain encodes the subjective value of pleasant and unpleasant situations via a single integrated circuit or through distinct pathways remains unresolved. It is also unclear how neural valu...

distinct roles of vmPFC and anterior insula high-frequency activity (>50hz) in tracking pleasant and unpleasant valuation

#iEEG
www.biorxiv.org/content/10.1...

Structure in noise: Recurrent connectivity shapes neural variability to balance perceptual and cognitive demands in the human brain Does neural variability reflect random noise or a feature that benefits adaptive behavior? Using intracranial recordings in humans, Terlau et al. demonstrate that neural variability results from the r...

New work from the lab published in @cp-neuron.bsky.social by @jonasterlau.bsky.social and Jan Martini. We describe that trial-by-trial variability indexes recurrent connectivity across the cortical hierarchy, which supports reliable and flexible coding www.cell.com/neuron/abstr... (1/4)

3 Postdoctoral Research Fellows Champalimaud Foundation (Fundação D. Anna de Sommer Champalimaud e Dr.

🚨Job alert🚨

The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour

This is part of a collaborative ARIA grant "4D precision control of cortical dynamics"

euraxess.ec.europa.eu/jobs/383909

A funny conversation with a newcomer at the contra dance in Woods Hole last night:
Me: What brings you to Woods Hole?
He: I’m a neuroscientist, working on octopuses.
Me: I’m a neuroscientist too! I study patches of human cortex that do ridiculously specific things.
He: Oh like that Kanwisher stuff?

New position, new social media account. After 5 fantastic years in Tuebingen, I moved to @yale.edu and the @wutsaiyale.bsky.social this summer - which means that I’ll be recruiting PhD students and postdocs. Please help me to spread the word and see current opportunities below 👇

Hippocampal stimulation reveals causal role of persistent neural activity in human working memory Working memory (WM) enables the temporary maintenance and manipulation of information, supporting flexible, goal-directed behavior. While converging evidence suggests that the hippocampus contributes ...

intracranial electrical stimulation on macro-electrodes & single-neuron recording from microwires. The sample size (N=30) is impressive. incredible work by Dr Jonathan Daume and Dr @urutisha.bsky.social and their colleagues.
www.biorxiv.org/content/10.1... #iEEG

A neural manifold view of the brain - Nature Neuroscience Recent advances in neuroscience have revealed how neural population activity underlying behavior can be well described by topological objects called neural manifolds. Understanding how nature, nurture...

Check out our new review/perspective (w/ @juangallego.bsky.social & Devika Narain) on neural manifolds in the brain! It was a lot of fun to think through these ideas over the past couple of years, and I'm excited it's finally out in the world!

🔗: www.nature.com/articles/s41...
📄: rdcu.be/ex8hW

Compositionality of social gaze in the prefrontal-amygdala circuits Each social gaze can be deconstructed into primitive components, including gaze content, social state, and gaze duration. To reduce dimensionality and facilitate generalization, the brain needs to rep...

Super excited to share this new work from the lab (led by Guangyao Qi)! We demonstrate compositional social gaze codes in the prefrontal-amygdala circuits, by testing three predictions from the compositionality hypothesis. 👇👇

www.biorxiv.org/content/10.1...

Direct interactions between the human insula and hippocampus during memory encoding Nature Neuroscience - The hippocampus and insula communicate when processing emotional memories. Discrete sites in the human insular cortex showed changes that predicted later memory recall, while...

Two brilliant studies combining intracranial recordings + intracranial electrical stimulation. Groundbreaking work from Josef Parvizi, Weichen Huang, Dian Lyu and colleagues! 🔥 #iEEG
rdcu.be/ew77E
rdcu.be/ew77I

The sycophantic tone of ChatGPT always sounded familiar, and then I recognized where I'd heard it before: author response letters to reviewer comments.

"You're exactly right, that's a great point!"

"Thank you so much for this insight!"

Also how it always agrees even when it contradicts itself.

Inter-brain neural dynamics in biological and artificial intelligence systems - Nature Shared inter-brain neural dynamics, reflecting aspects of social interaction including self and other’s behaviours, arise in GABAergic neurons of the dorsomedial prefrontal cortex of socially interact...

Nature

Inter-brain neural dynamics in biological and artificial intelligence systems

www.nature.com/articles/s41...

thanks for sharing our work : )

Simultaneous intracranial recordings of interacting brains reveal neurocognitive dynamics of human cooperation - Nature Neuroscience Using intracranial recordings in pairs of humans cooperating in interactive games, this study shows fine-grained cooperation dynamics featured by state-dependent motives and the intrabrain and interbr...

Nature Neuroscience

Simultaneous intracranial recordings of interacting brains reveal neurocognitive dynamics of human cooperation
www.nature.com/articles/s41...

New nat. commun. Paper by Cecchi et Al. 2024 on Causal involvement of anterior insulate and ventrimedial prefrontal cortex during risky choices

rdcu.be/dSn7I

Four years of work: congrats to romane: well done !!