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Zechner Lab

@zechnerlab

Research group at SISSA / Trieste. Interested in stochastic processes in biology & biophysics. Posts by C. Zechner.

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01.03.2024
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Latest posts by Zechner Lab @zechnerlab

Our work on the interplay between loop extrusion and chromatin mechanics is finally out in @physrevresearch.bsky.social . Congrats @hosseinsalari.bsky.social for the hard work ! πŸ‘
journals.aps.org/prresearch/a...

23.02.2026 13:00 πŸ‘ 17 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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Come on join us! We are searching for the next technical associate to join our lab ~Summer 2026.

This could be a great position for someone who is graduating this spring and is looking for 2 more years of research experience before starting their PhD:
careers.peopleclick.com/careerscp/cl...

11.02.2026 21:09 πŸ‘ 17 πŸ” 11 πŸ’¬ 0 πŸ“Œ 1
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The EMBO Young Investigator Network consists of young investigators, installation grantees and global investigators. πŸ§ͺ

Find more information on the individual programmes here:
https://www.embo.org/the-embo-communities/embo-young-investigator-network/
#LifeSciences #research #funding

02.02.2026 06:55 πŸ‘ 8 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧡 and at www.nature.com/articles/s41... 🀩
@poldresden.bsky.social @mpi-cbg.de

07.01.2026 16:02 πŸ‘ 150 πŸ” 60 πŸ’¬ 8 πŸ“Œ 5
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Dynamics of microcompartment formation at the mitosis-to-G1 transition - Nature Structural & Molecular Biology Goel et al. produce high-resolution three-dimensional genome structure mapping from mitosis to G1 phase to show unseen interactions between enhancers and promoters in prometaphase. Polymer modeling in...

See this recent paper by @andersshansen.bsky.social that discovers similar microcompartmentalization during mitotic exit:

www.nature.com/articles/s41...

22.12.2025 11:45 πŸ‘ 9 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
Call for Applications, Postgraduate Diploma Programme | ICTP Are you a student who dreams of earning a PhD in physics or mathematics, but who lives in a country lacking such opportunities? ICTP could be your first step on the path to attaining a PhD.

An incredible ICTP initiative is our Postgraduate Diploma Programme. Rigorous one-year pre-PhD training for students from the Global South. I have personally seen this program transform the lives of those in the quant life sciences.

Due Feb. 28 2026. Please share widely.
www.ictp.it/news/2025/11...

18.12.2025 12:53 πŸ‘ 7 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
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Size control guidelines for chemically active droplets Biological cells and synthetic analogues use liquid-liquid phase separation to dynamically compartmentalize their environment for various applications. In many cases, multiple droplets need to coexist...

Since more than a decade, our group has been exploring chemically active droplets, which are exciting since their size can be controlled. Yet, we still do not fully understand this control even in the simplest models. Until a new preprint (arxiv.org/abs/2512.02542) spearheaded by postdoc Guido...

15.12.2025 08:07 πŸ‘ 12 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
University Assistant/Associate Professor in Control Theory and Systems Biology Applications are invited for a University Assistant/Associate Professorship in the broad area of Control Theory and Systems Biology. The successful candidate will join the Control Group

We are opening a FACULTY POSITION (tenure track, permanent) in the University of Cambridge at the interface of control and biology, interpreted broadly. Theorists and wet lab quantitative biologists with backgrounds in control, EE, applied math, ... apply by Jan 28!

www.cam.ac.uk/jobs/univers...

03.12.2025 12:19 πŸ‘ 42 πŸ” 41 πŸ’¬ 0 πŸ“Œ 1

Congrats Jesse, very well deserved!!

02.12.2025 16:37 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

I am honored and proud to work with my amazing group @mpi-cbg.de and @csbdresden.bsky.social πŸ₯° 🧬. Thanks to all my colleagues for the wonderful scientific environment. And thank you @kboes.bsky.social for preparing this superb video! 🀩

01.12.2025 09:17 πŸ‘ 17 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0

The most precious commodity you have is your attention. You don’t have to waste it on poor-faith debates or arguments with strangers if you don’t think they’ll be productive. You can prioritize the things that matter to you and make your life richer.

30.11.2025 20:00 πŸ‘ 11821 πŸ” 3004 πŸ’¬ 131 πŸ“Œ 196

I’m very excited to start this project β€” it brings together ideas that matured over many years and opens a long-term path for innovation in RNA modelling. 🍾 🧬

28.11.2025 13:36 πŸ‘ 8 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

One of our founding directors Anthony Hyman @hymanlab.bsky.social will become @embl.org Director General: www.mpi-cbg.de/news-outreac...

27.11.2025 13:20 πŸ‘ 62 πŸ” 14 πŸ’¬ 1 πŸ“Œ 0
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Wonderful to see the beautiful preprint from Sabate et al now published - TADs are also dynamic structures in human cells, with remarkably similar parameters between mESCs and HCT116 cells
www.nature.com/articles/s41...

15.11.2025 17:24 πŸ‘ 38 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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Postdoc in Theoretical Biophysics Two postdoc positions (each for two years, funded by Amidex Foundation) are available in theoretical biophysics within the theory group at DyNaMo (Aix-Marseille University).

Two 2-year postdoc positions in my theory group β€” for studying the interplay between metabolism and morphogenesis at the edge of the Calanques and the Mediterranean. More information can be found on: euraxess.ec.europa.eu/jobs/381176
#biophysics

27.10.2025 16:19 πŸ‘ 5 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

Really excited to share our latest work led by @mattiaubertini.bsky.social and @nesslfy.bsky.social: we report that cohesin loop extrusion creates rare but long-lived encounters between genomic sequences which underlie efficient enhancer-promoter communication.
www.biorxiv.org/content/10.1...
AπŸ§΅πŸ‘‡

24.09.2025 21:45 πŸ‘ 114 πŸ” 52 πŸ’¬ 8 πŸ“Œ 5

Thanks a lot to @elisecutts.bsky.social for nicely highlighting and putting in context our article! It was very interesting to discuss together, notably about the analogies between the emergence of order in Hydra and other physical phenomena.

12.09.2025 13:56 πŸ‘ 16 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

Great work! Congratulations you all & especially to
@carldmodes.bsky.social who joined today after a lot of arm twisting by Caren...

22.08.2025 14:13 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...

21.08.2025 05:18 πŸ‘ 345 πŸ” 130 πŸ’¬ 31 πŸ“Œ 23
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Our beautiful Hydra made the cover!!! 😍😍😍
An experiment performed by Pavel Mejstrik with a HCR protocol by @giuliaserafini.bsky.social, @paveltomancak.bsky.social lab @mpi-cbg.de
Actin fibers in blue, nuclei in orange.

13.08.2025 08:51 πŸ‘ 154 πŸ” 25 πŸ’¬ 3 πŸ“Œ 0

Our first #Hydra paper. @anaisbailles.bsky.social all the way, with crucial theory contributions from Carl Modes and @zechnerlab.bsky.social Hydra maintenance by Heino Andreas and HCR by Giulia Serafini. Teamwork. Many thanks to the generous Hydra research community.

06.08.2025 15:13 πŸ‘ 58 πŸ” 14 πŸ’¬ 2 πŸ“Œ 1
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Stretching the immortal Hydra Dresden researchers show how cells can create a new organism from scratch by coordinating their mechanical properties.

Stretching the immortal Hydra. Publication by @paveltomancak.bsky.social group with Carl Modes @mpi-cbg.de & @zechnerlab.bsky.social shows how cells can create a new organism from scratch by coordinating their mechanical properties. @anaisbailles.bsky.social @pnas.org www.mpi-cbg.de/news-outreac...

05.08.2025 12:45 πŸ‘ 46 πŸ” 16 πŸ’¬ 1 πŸ“Œ 0
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Novel Research in Biological Artificial Intelligence Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence.

Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...

26.06.2025 11:26 πŸ‘ 32 πŸ” 29 πŸ’¬ 0 πŸ“Œ 3

We are searching for an AI researcher in lab automation, statistical ML and (theoretical) physics AI for bio/med. Expression of interest and nominations welcome!!!

26.06.2025 21:10 πŸ‘ 3 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
Friedrich Miescher Institute, open position Friedrich Miescher Institute, open position

We are looking for a research assistant to join our lab and support ongoing projects with genome engineering in mouse embryonic stem cells! Please get in touch if you are interested.
www.fmi.ch/education-ca...

26.06.2025 15:04 πŸ‘ 19 πŸ” 22 πŸ’¬ 0 πŸ“Œ 0
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(1/n) Thread @matteomazzocca.bsky.social @domenicnarducci.bsky.social Simon Grosse-Holz @jessematthias.bsky.social preprint

Q: how does chromatin move?

Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide answers www.biorxiv.org/content/10.1...

15.05.2025 12:37 πŸ‘ 68 πŸ” 22 πŸ’¬ 2 πŸ“Œ 1
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Many congratulations to Anne for defending her PhD this week…excellent results and presentation! We wish you all the best for your future career!

28.03.2025 08:51 πŸ‘ 7 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

We are finalizing the program of the @cecamevents.bsky.social RNA modelling across scales www.cecam.org/workshop-det... at SISSA, Trieste, Italy, May 19-22. Please note that we still have a few slots for in person attendance. We will accept applications for the next few weeks, until fully booked!

27.03.2025 17:15 πŸ‘ 11 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
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Come to #Prague for #Woodstock2025. What is it? A scientific conference unlike any other. Think #BurningMan or #MusicFestival but #science themed. It'll have two parts - decentralised sessions spread in #Prague (sightsee as you move around) & #campsite event to wrap it up (1/7)

02.03.2025 11:52 πŸ‘ 38 πŸ” 18 πŸ’¬ 3 πŸ“Œ 1
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"Cacio e pepe" physics: In arxiv.org/abs/2501.00536v1, eight Italian scientists from the Max Planck Institute for the Physics of Complex Systems explain the physics behind a perfect dish of "cacio e pepe" and how to eschew the dreaded "mozzarella phase" - work featured @nytimes.com.

29.01.2025 20:50 πŸ‘ 30 πŸ” 8 πŸ’¬ 1 πŸ“Œ 1