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Cristian Mesquida

@crist14n

Postdoctoral researcher at Eindhoven University of Technology. Having a great time doing meta-research.

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18.11.2023
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Latest posts by Cristian Mesquida @crist14n

Non-adherence is central to therapy research, and it's among the primary reasons I like ITT. Removing non-adherent persons from a therapy RCT would result in a causal estimand that has less relevance to real-world therapy than otherwise. Real world therapy clients don't perfectly comply.

27.02.2026 02:40 πŸ‘ 3 πŸ” 1 πŸ’¬ 3 πŸ“Œ 0
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New workshop announced: Advanced Basic Statistics Workshop: Deepening Your Understanding of Standard Statistical Analyses | Paul Meehl Graduate School We are excited to announce that registration is now open for the workshop, β€œAdvanced Basic Statistics Workshop: Deepening Your Understanding...

New Paul Meehl Graduate School course: Advanced Basic Statistics Workshop: Deepening Your Understanding of Standard Statistical Analyses

March 27, 2026

Sign up:
paulmeehlschool.github.io/2026-02-23-a...

26.02.2026 18:25 πŸ‘ 11 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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Lovely day in Eindhoven, and not just because of the weather! I had Maciej Behnke over as visitor for a few days to talk science and pick up an old collaboration! And @crist14n.bsky.social had Jenny Murphy, Simon Nolte, and Robert Rein over to talk computational reproducibility in Sports science.

25.02.2026 18:12 πŸ‘ 10 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

@jennymurphy2.bsky.social

25.02.2026 18:35 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
10Β  Sequential Analysis – Improving Your Statistical Inferences This open educational resource contains information to improve statistical inferences, design better experiments, and report scientific research more transparently.

The lack of uptake of sequential analysis shows how irrational scientists are, and how their methods are driven by norms. Sequential analyses give you more flexibility and are more efficient than a single hypothesis test, and yet, they are still very rare. lakens.github.io/statistical_...

23.02.2026 16:59 πŸ‘ 11 πŸ” 4 πŸ’¬ 2 πŸ“Œ 0
Make Existing R Code Reproducible with 'worcs' and 'targets'
Make Existing R Code Reproducible with 'worcs' and 'targets' YouTube video by Caspar van Lissa

Does your R-script work on your computer? Want to make it fully reproducible on ANY system, now and in the future? In this video, I demonstrate how to turn R scripts into reproducible, version-controlled projects with worcs, renv, targets, and testthat to verify reproducibility. youtu.be/3mgRFMr5APU

23.02.2026 09:03 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Does anodal tDCS over M1 really enhance motor sequence learning? A non-replication of earlier findings in a double-blind, pre-registered large-sample study in humans Background Transcranial direct current stimulation (tDCS) is one of the most widely used noninvasive neuromodulation methods. Despite its popularity, some recent studies highlighted issues about the r...

One of my two last (ever) papers on tDCS:
Does anodal tDCS over M1 really enhance motor sequence learning? A non-replication of earlier findings in a double-blind, pre-registered large-sample study in humans
www.medrxiv.org/content/10.1...

11.10.2025 09:35 πŸ‘ 35 πŸ” 17 πŸ’¬ 4 πŸ“Œ 2
Conference –

Call for Submissions for the Theory Methods Conference 2026, September 30-October 2! theorymethodssociety.org/conference.h...

We invite you to:
1) Submit your proposal: edu.nl/mj9x6
2) Invite your colleagues/lab/(PhD) students, and encourage them to submit
3) Share this post

20.02.2026 09:27 πŸ‘ 19 πŸ” 21 πŸ’¬ 1 πŸ“Œ 0
Positron workflows that make life easier | Andrew Heiss | Data Science Lab
Positron workflows that make life easier | Andrew Heiss | Data Science Lab YouTube video by Posit PBC

@andrew.heiss.phd joined us on the DS Lab, shared his screen with us, and spilled all of his secrets. You REALLY want to watch this: youtu.be/kqYbJoebrwE (links galore in the description!)

And follow along with all the tools he mentions here on his blog post: andhs.co/dsl

#databs #rstats #Positron

18.02.2026 05:49 πŸ‘ 25 πŸ” 4 πŸ’¬ 1 πŸ“Œ 2
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We continue with James Steele (wearing his 'stay calm and read Paul Meehl' shirt) who is in a high pace running us through his views on how we develop and test strong theories. #PSE8

12.02.2026 09:02 πŸ‘ 18 πŸ” 3 πŸ’¬ 1 πŸ“Œ 2
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Introduction to INSPECT-SR Training Workshop March (Europe) An introductory 2-hour online workshop will introduce participants to the INSPECT-SR tool for assessing trustworthiness of randomised controlled...

Next free online INSPECT-SR training workshop on March 6th. Register here: www.trybooking.com/uk/FZUN Timed for Europe. Will try to add something for North America in the next few days...

10.02.2026 16:57 πŸ‘ 7 πŸ” 6 πŸ’¬ 0 πŸ“Œ 1
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The case for sharing clinical trial data The story behind the first statin and how its development was almost derailed, and the implications of sharing clinical trial data.

New short blogpost!

There are probably many benefits of sharing clinical trial data, including:

Verifying results, better meta-analysis, understanding inconsistent results, further exploration, better clinical decision-making, learning how to run trials better, and reducing redundancy.

09.02.2026 22:04 πŸ‘ 44 πŸ” 13 πŸ’¬ 2 πŸ“Œ 2
What's Missing? 300 extensions and counting. Help shape what comes next.

What's Missing? 300 extensions and counting. Help shape what comes next.

What Quarto extension would make your workflow easier?

There are already almost 300 extensions browsable at m.canouil.dev/quarto-exten... and installable via Quarto Wizard at m.canouil.dev/quarto-wizard/.

Drop your ideas below.
If there's enough interest, I might just build it.
#Quarto #OpenSource

29.01.2026 13:16 πŸ‘ 27 πŸ” 9 πŸ’¬ 2 πŸ“Œ 1
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Introducing Causion: A web app for playing with DAGs | Peder M. Isager Personal website of Dr. Peder M. Isager

New blog post introducing Causion - a web app for causal inference teaching and learning: pedermisager.org/blog/causion....

28.01.2026 09:23 πŸ‘ 144 πŸ” 66 πŸ’¬ 5 πŸ“Œ 6
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Confusion in gaming disorder measurement Abstract. Measurement is important for the scientific programmes of addictive behaviours. In the present study, we investigated the measurement of gaming d

First post of the year, new paper out today: we present possibly the biggest case of systematic Measurement Schmeasurement in tech use. It seems that most studies on gaming (videogame) addiction/disorder haven't measured gaming after all. This research took years, so long 🧡 doi.org/10.1098/rsos...

28.01.2026 09:56 πŸ‘ 193 πŸ” 100 πŸ’¬ 8 πŸ“Œ 20
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RegCheck RegCheck is an AI tool to compare preregistrations with papers instantly.

Comparing registrations to published papers is essential to research integrity - and almost no one does it routinely because it's slow, messy, and time-demanding.

RegCheck was built to help make this process easier.

Today, we launch RegCheck V2.

🧡

regcheck.app

22.01.2026 11:05 πŸ‘ 174 πŸ” 90 πŸ’¬ 8 πŸ“Œ 6

Is anyone here an expert on #rstats ellmer structured data?

It works when I define the JSON schema of an object A containing an array of object B, but not when I read object B from JSON schema and use type_object and type_array to set up object A.

Reprex: gist.github.com/debruine/d35...

20.01.2026 11:48 πŸ‘ 1 πŸ” 8 πŸ’¬ 1 πŸ“Œ 0
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PSE8 - Preliminary Program, Leiden - Feb 11-13 8th Perspectives on Scientific Error Workshop February 11th–13th, 2026, Leiden (Rapenburg 73), The Netherlands Conference website: https://perspectivesonscientificerror2026.wordpress.com/ …

The full program of the Perspectives on Scientific Error conference is live! perspectivesonscientificerror2026.wordpress.com Keynotes: Leif Nelson about catching liars, Vlasta Sikimić about Science in the Age of AI, Frantiőek Bartoő on Robustness Reports, and Femke Truijens on error in methods.

20.01.2026 18:54 πŸ‘ 18 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0

Here it is! #rstats

19.01.2026 20:50 πŸ‘ 34 πŸ” 10 πŸ’¬ 0 πŸ“Œ 0
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a cartoon of donald duck says " and a bah humbug " to you ALT: a cartoon of donald duck says " and a bah humbug " to you

Our publishing system does not prioritise or value the careful curation of research data to be FAIR nearly enough. I have been data editing for AP&P for a year now, and it is sad to see no reward for the clearly careful organisation of data and materials vs that which is thrown on OSF with no care!

18.01.2026 02:33 πŸ‘ 24 πŸ” 5 πŸ’¬ 1 πŸ“Œ 1
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PSE8 Visit the post for more.

The program for the Perspectives on Scientific Error conference Februari 11 to 13 in Leiden is online!
Registration is open! perspectivesonscientificerror2026.wordpress.com

This is one of the most inspiring and fun metascience meetings around - lots of time to interact, great talks - so do come!

12.01.2026 10:49 πŸ‘ 26 πŸ” 15 πŸ’¬ 1 πŸ“Œ 1
PubPeer - Large-scale investigation confirms TRPM3 ion channel dysfunc... There are comments on PubPeer for publication: Large-scale investigation confirms TRPM3 ion channel dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (2026)

Pseudoreplication is a common issue in biomedical studies, Nicely illustrated here: pubpeer.com/publications...

And good explainer, with R code for analysing such data here:
www.wiley.com/en-ie/Basic+...

#statistics

13.01.2026 09:37 πŸ‘ 17 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
Scientific Criticism and Peer Review | Paul Meehl Graduate School January 30, 2026

You can sign up until January 23 for the free Paul Meehl Graduate School workshop on Scientific Criticism and Peer review taught by RenΓ© Bekkers. It promises to be an extremely interesting day, so do join us in Eindhoven on January 30th! paulmeehlschool.github.io/workshops/cr...

09.01.2026 19:29 πŸ‘ 11 πŸ” 13 πŸ’¬ 0 πŸ“Œ 0
Assessing the properties of the prediction interval in random-effects meta-analysis | Research Synthesis Methods | Cambridge Core Assessing the properties of the prediction interval in random-effects meta-analysis

β€œAssessing the properties of the prediction interval in random-effects meta-analysis” www.cambridge.org/core/journal...

10.01.2026 07:10 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
An Open Letter to the BMJ Editorial Board to: Editor in chief, Kamran Abbasi , kabbasi@bmj.com Β  Β  Β Executive editor, Theodora Bloom , tbloom@bmj.com Β  Β  Β Head of research, Elizab...

How long should it take to retract a paper with incontrovertible signs of data fabrication? Sleuths think 2 months is too long, particularly when clinical risks are involved. deevybee.blogspot.com/2026/01/an-o...
#retraction #stemcells #cardiology
@erictopol.bsky.social

05.01.2026 09:38 πŸ‘ 70 πŸ” 32 πŸ’¬ 1 πŸ“Œ 7
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27 studies re-examined | Open Science NL Open Science NL has awarded funding to 27 applicants to replicate earlier studies. They will reanalyse original data, repeat experiments, and replicate studies with slight variations to the original…

Very happy to have received a replication grant from NWO! We will be reproducing power analyses of large scale replication projects, to learn how to improve power analyses, and increase quality control in large team Science projects! www.openscience.nl/en/news/27-s...

17.12.2025 15:05 πŸ‘ 65 πŸ” 9 πŸ’¬ 2 πŸ“Œ 1
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Cycling like the Dutch would slash the world’s carbon footprint If everybody cycled like the Dutch, we could offset the UK or Australia’s entire carbon footprint.

β€œDutch people cycle an average of 2.6km each per day. If this pattern was replicated worldwide, annual carbon emissions would drop by 686 million tonnes.

This mammoth figure exceeds the entire carbon footprint of most countries, including the UK, Canada, Saudi Arabia and Australia.” @euronews.com

13.12.2025 22:01 πŸ‘ 1350 πŸ” 493 πŸ’¬ 47 πŸ“Œ 58
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No, PCOS Doesn't Lower BMR (Scientific Review) This article examines the roots of the claim that women with PCOS have a lower BMR and reviews the research on the subject.

So, folks might recall the great BMR series of articles from the MacroFactor team last year. One of the articles tackled the challenges women with polycystic ovary syndrome (PCOS) face with respect to managing their weight, and claims that this is in part due to "slower metabolism"

🧡1/7

08.12.2025 10:49 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Preserving musculoskeletal health through resistance training in individuals undergoing Glucagon-like Peptide-1 Receptor Agonist Therapy: a controlled interrupted time-series analysis (Stage 1 Registe... Glucagon-like peptide-1 receptor agonists (GLP-1-RAs) are increasingly prescribed for weight loss and cardiometabolic health but have been evidenced to lead to loss of lean soft tissue mass. Resistanc...

Just had our first set of reviews from @pci-regreports.bsky.social for our proposed study on RT during GLP-1-RA treatment.

Probably the most constructive and useful set of reviews I have ever had... and having them before starting the study makes them even better!

11/10 would recommend!

04.12.2025 10:42 πŸ‘ 23 πŸ” 8 πŸ’¬ 1 πŸ“Œ 0

Metacheck can now automatically 1) download a preprint from PsyArXiv, 2) create a report of the checks (stats, reporting guidelines, references, code, etc), 3) retrieve the authors email, and 4) send them the report.

Would you as an author appreciate this? When yes, when no?

02.12.2025 18:12 πŸ‘ 25 πŸ” 7 πŸ’¬ 4 πŸ“Œ 2