Vincent J Lynch 🐘🦣🦥 🦇🐋🐢🐍

Pretty funny he thinks drink orders are too individualized, while using the language of tailored goods; bet he has a tailored suit....

A striking digital composite celebrating Ada Lovelace, the world's first computer programmer. On the left is a vibrant, colorized restoration of her iconic 1838 portrait, showing her in a deep purple velvet gown with white lace accents and an elegant headdress. She gazes with sharp, visionary intelligence toward the right of the frame. Occupying the right side of the image is the intricate mechanical hardware of the Analytical Engine trial model - a complex assembly of vertical brass rods, interlocking gears, and polished metal dials. Floating subtly over the mechanical parts is a translucent overlay of her handwritten 1843 Bernoulli algorithm (Note G), showing the logical mathematical table that served as the world's first software. The composite beautifully illustrates the transition from 19th-century mechanical engineering to the birth of modern computing, representing Ada’s unique philosophy of "Poetical Science." The lighting unifies the historical portrait and the brass machinery into a single, cohesive moment of discovery. Credit: Seriously Scientific.

Remembering Ada Lovelace on International Women's Day!

A century before computers, she saw that machines could do more than just math.
By writing the first algorithm for the Analytical Engine, she became the world’s first programmer and predicted the digital age we live in today!💻
#WomenInScience

a cartoon of a lion with the words leo power on it ALT: a cartoon of a lion with the words leo power on it

lol. I did say “most of the time‽” Not that it was deterministic :-)

Rationalist materialist here, yet somehow the zodiac signs seems to be spot on most of the time‽ ♌️

Amy Goldberg, PhD - Join The Goldberg lab is moving to UCLA summer 2025, and recruiting postdocs and graduate students. We are a computational lab with occasional wet lab or field collaborators. We will be located in the Department of Human Genetics in the Geffen School of Medicine at UCLA. With the knowledge that

UCLA's Goldberg lab seeks postdocs for projects in population genetics, ecology, and more. Flexible start date, fully funded. Interested candidates should contact Amy Goldberg. Details: https://www.goldberglab.org/join #postdoc

Which Star Trek series‽

It’s the second post that’s the banger 🫠

The Rodent With a Desert on its Shoulders In a refuge rarely visited by people, California’s giant kangaroo rat helps other species thrive.

Gorgeous essay on my previous study critter and site🧪🌏 www.biographic.com/the-rodent-w...

Thank you, @emptywheel.bsky.social for flagging this post to me. I took a close look at another data source, and this plane appears to have made a stop in Dubai. Probably didn't show up on ADSBx bc some of their feeders are down and there is a lot of signal jamming in the region rn.

HOWEVER, 1/

If you’re at #dros26 and you like transposons don’t miss Peiwei’s talk! 🔥🪰 We’re really excited about his findings!

William Whewell, influential British polymath & philosopher, coined words physicist & scientist, proposed new terminology for discoveries in chemistry by Faraday & in geology by Lyell. Mentioned in Trollope’s Barchester Towers; died #OTD 1866.
Professor, Master, Chancellor Trinity College Cambridge

I’m glad NPR included skeptical voices - because de-extinction is a dangerous fantasy - but we’ve seen this before. Colossal dangles a story/access, journalists take it and say other researchers have criticisms, and nothing changes save for an update to the I Can’t Believe It’s Not Mammoth! timeline

I teach a segment on conservation genetics in my molecular ecology class. My favorite moment is when my students realize that Colossal is just a bunch of conservation grifters. Technically, these guys would make more money by MORE species going extinct.

The science is as over-hyped and borderline fraudulent as the ethics are thorny (and that doesn't even count the George Church, friend of Epstein angle)

If you're doomscrolling, guess what? So far there are 51 kākāpō chicks hatched and thriving this season, the same number of birds as we had in TOTAL in the 90s! Only one chick has died and there are still fertile eggs waiting to hatch!

You’d know better than I!

Thomas Hurd (Univ Toronto) @tomhurd on how paternal mtDNA gets “cut out of inheritance”; 100s of mtDNA in oocyte but <1 per sperm; this elimination takes place within spermatogenesis from immature to mature sperm; mtDNA eliminated but not mitochondria themselves (sperm need energy to swim) #Dros26

Very cool! Almost all mitochondria in sperm are in the middle piece no? So by limiting which part of the sperm gets into the egg limits parental mt inheritance?

Food is politics. It always has been. Fancy food all the more so…

If memory serves this is one of the differences Cuvier used described mammoths as distinct from extant elephants no?

Laying of hands would be a really bad idea if so…

2-1-2-3
-———-
2-1-2-3

eh, there is a post not found error?

The Extinction of Truth Or, a Colossal Pile of Bullshit

Apropos the obvious...

substack.com/@devoevomed/...

A comprehensive genomic history of extinct and living elephants | PNAS Elephantids are the world&rsquo;s most iconic megafaunal family, yet there is no comprehensive genomic assessment of their relationships. We report a tot...

lol, we did some stuff. This is also a good reference:

www.pnas.org/doi/10.1073/...

Memory does not serve. They claim 65.

colossal.com/mammoth/

I recall reading somewhere that the number of edits they were making was in the mid-20s (if my memory serves me right).

A reminder that captive births are very far from risk free in elephants. You cannot do a c-section if e.g. development or delivery goes wrong (=death to mum for sure).

Honestly, this would not pass an ethics committee in the UK, I am sure.

I hope this is just more of the usual nonsense

If the first Lammoth is two years away, that means gene-edited embryos are about to be implanted into surrogates any time now.

I have always argued that the use of elephants in experiments like this is unethical.

My opinion has not changed.