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Robert Jansen

@robertsjansen

Assistant Professor in microbial metabolism at Radboud University. I explore new functions of enzymes and metabolites using untargeted metabolomics and like to ๐Ÿƒ www.functional-metabolomics-lab.nl

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25.12.2024
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Latest posts by Robert Jansen @robertsjansen

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Subsidy for research using microorganisms to recycle critical metals | Radboud University Microbiologist Martyna Glodowska is working on a way to recover critical metals from waste materials such as e-waste, by using the power of microorganisms and biogeochemical processes.

An international team of researchers led by microbiologist Martyna Glodowska will use microorganisms to recover scarce metals from electronic waste. ๐Ÿฆ  The research team is receiving a grant of up to โ‚ฌ1.5 million from the SPRIND Tech Metal Transformation Challenge. Read more www.ru.nl/en/research/...

09.03.2026 09:21 ๐Ÿ‘ 5 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Postdoctoral Researcher in Environmental and Analytical Chemistry (f/m/d) 60 - 100 % The Department of Environmental Chemistry (Uchem) of Eawag is offering a position for a

#postdoc #job Environ Analytical Chemistry & Toxicology of #benthic #cyanobacteria @eawag.bsky.social Eawag in #Switzerland! Creating knowledge base of benthic cyanobacteria in Switzerland in collaboration with Pilar Junier Uni.Neuchatel. apply by April 8th.
apply.refline.ch/673277/1346/...

07.03.2026 14:06 ๐Ÿ‘ 3 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Job Details

Pls re-post: My department @oxfordbiochemistry.bsky.social are recruiting for several new faculty positions (links below). Broad search in molecular biology/biochemistry, across prokaryotes and eukaryotes. Interested in understanding life at the molecular level, this job might be for you!
1/n

05.03.2026 21:35 ๐Ÿ‘ 87 ๐Ÿ” 125 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 3
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The metabolome of an E. coli CRISPRi library identifies benefits of minimal metabolite levels and targets for engineering Rapp et al. combine genome-scale CRISPRi and metabolomics in E. coli. CRISPRi of enzymes enforces metabolite accumulation, which leads to regulatory crosstalk and side reactions. This suggests that ma...

Technically this required metabolomics on ~3,000 samples from an arrayed CRISPRi library.

The bottleneck wasnโ€™t MS or sampling.

It was sequencing the strains after arraying.

Paper: www.cell.com/cell-systems...

05.03.2026 16:55 ๐Ÿ‘ 3 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Multi-omics reveals nitrogen dynamics associated with soil microbial blooms during snowmelt Nature Microbiology, Published online: 27 January 2026; doi:10.1038/s41564-025-02213-2Soil microbial populations bloom and then die-off in ecosystems with seasonal snowpack. This study showed that distinct taxa utilize different N sources for growth or energy during the microbial bloom and alter the fate of N after snowmelt.
04.03.2026 05:28 ๐Ÿ‘ 9 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

We are searching for a tenure-track junior faculty member. Join our collaborative research environment in the Department of Microbiology and Immunology at WCM. Please see the link to the job posting and distribute among your networks!
apply.interfolio.com/181869

02.03.2026 15:15 ๐Ÿ‘ 7 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Current meeting | ESM

๐Ÿš€ #ESM2026 registration is open! 46th Annual Congress of the European Society of Mycobacteriology.
๐Ÿ“ Verona, Italy | ๐Ÿ—“๏ธ 22โ€“25 June 2026
๐Ÿ”— www.esmycobacteriology.eu/event-home

01.03.2026 08:54 ๐Ÿ‘ 2 ๐Ÿ” 3 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Four more days left to apply or share with your network.

For the 2 postdoc offers in experimental evolution, apply here: fa-eosd-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/Candid...

For the 2 PhD offers in electromicrobiology, apply here: fa-eosd-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/Candid...

01.03.2026 12:42 ๐Ÿ‘ 1 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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A novel North Sea ammonia-oxidizing archaeon Nitrosarchaeum marinum leverages a high abundance of transport systems to grow over a wide salinity range Isolation and characterization of a novel North Sea ammonia oxidizing archaeon, Nitrosarchaeum marinum T12, reveals an adaptation to a broad salinity under

Long in the making, great to see the study on line at @femsmicro.org A novel North Sea ammonia-oxidizing archaeon Nitrosarchaeum marinum leverages a high abundance of transport systems to grow over a wide salinity range. #microbiology @ribesresearch.bsky.social academic.oup.com/femsec/artic...

01.03.2026 07:50 ๐Ÿ‘ 15 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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And The Microbes

OH MY GOSH I JUST FOUND THIS ๐Ÿ˜ƒ

www.andthemicrobes.org

#comic #bacteria #phage #plasmids ๐Ÿฆ 

25.02.2026 11:24 ๐Ÿ‘ 12 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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PhD candidate in Equine Intestinal Microbiome and Resistome Join this PhD project to study how the equine gut microbiome and resistome can improve gastrointestinal health and combat antimicrobial resistance.

Our faculty has a particularly interesting PhD position open on antimicrobial resistance, effects of antibiotics treatment on the microbiome and resistome, restoration of the equine microbiome using FMT.

www.uu.nl/en/organisat...

Please contact Mathijs Theelen, email address in the link below.

24.02.2026 12:10 ๐Ÿ‘ 25 ๐Ÿ” 24 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Beautiful and solid work on trehalose monomycolate synthesis in mycobacteria by @figlegend.bsky.social lab. Check it out folks. Also, for the non-enzymologists, product inhibition is a thing, and actually does matter. ๐Ÿ˜œ

www.pnas.org/doi/10.1073/...

24.02.2026 17:53 ๐Ÿ‘ 14 ๐Ÿ” 5 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

There are just a few days left to apply. #Tuberculosis ๐Ÿงช๐Ÿฆ  #TBDrugDiscovery

24.02.2026 17:29 ๐Ÿ‘ 1 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Two postdoctoral positions (3-year) in Experimental Evolution of Methanogenic Microbiomes in Bioelectrochemical Systems Application deadline: 4 March 2026 at 23:59 hours local Danish time

Hiring: two 3-year Postdoc positions

Weโ€™re looking for postdocs who can design and run directed laboratory evolution experiments in microbial communities under electrochemical stimulation, and link adaptations to performance using shotgun meta-omics.

23.02.2026 05:45 ๐Ÿ‘ 8 ๐Ÿ” 10 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Cell-free genomics reveals fundamental regulatory principles of the Mycobacterium tuberculosis transcription cycle Tiers of gene regulation govern cellular life. The intrinsic activities of RNA polymerase (RNAP) constitute a primary tier, while direct modulation byโ€ฆ

Congrats Ruby, Bob, Liz, and team! www.sciencedirect.com/science/arti...

19.02.2026 16:21 ๐Ÿ‘ 8 ๐Ÿ” 3 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 2
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Finally out in @nature.com: a new piece of the puzzle of how complex life evolved. Lead by @archaeal.bsky.social & @katyappler.bsky.social. Great collab with @greening.bsky.social and @kassipan.bsky.social. More pieces to follow soon! www.nature.com/articles/s41...

18.02.2026 17:59 ๐Ÿ‘ 82 ๐Ÿ” 30 ๐Ÿ’ฌ 4 ๐Ÿ“Œ 0
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Meer dan mooie woorden: de universiteit heeft een strategie nodig met radicaal vertrouwen en een biologisch fundament - Vox magazine OPINIE - De nieuwe strategie van de Radboud Universiteit ontvouwt zich als een gedurfde visie die de traditionele bescheidenheid van zich afschudt, schrijft hoogleraar microbiologie Mike Jetten. Maar ...

OPINIE - De nieuwe strategie van RU is een gedurfde visie die de bescheidenheid van zich afschudt, schrijft Mike Jetten : 'we kunnen het ons niet veroorloven een generatie briljante talenten te verliezen omdat ze te uitgeput zijn door bureaucratie & gebrek aan budgetten www.voxweb.nl/opinie/meer-...

18.02.2026 10:06 ๐Ÿ‘ 6 ๐Ÿ” 5 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
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๐Ÿ“ข 4-year PhD position in my lab at @crick.ac.uk

Using active learning & chemical genomics to find new antibiotics with new targets in pathogenic bacteria.

Looking for: chemistry / chem bio / comp bio / micro backgrounds with coding interest.

Deadline 17 March.

www.crick.ac.uk/careers-stud...

17.02.2026 18:55 ๐Ÿ‘ 3 ๐Ÿ” 3 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 0

14 more days left to apply for these two PhD positions in my team. Please share with your network!

17.02.2026 09:31 ๐Ÿ‘ 6 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Navigating the conjugated metabolome https://www.biorxiv.org/content/10.64898/2026.02.06.704496v1

10.02.2026 05:46 ๐Ÿ‘ 2 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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ChemEmbed: a deep learning framework for metabolite identification using enhanced MS/MS data and multidimensional molecular embeddings Abstract. Machine learning offers a promising path to annotating the large number of unidentified MS/MS spectra in metabolomics, addressing the limited cov

ChemEmbed: a deep learning framework for metabolite identification using enhanced MS/MS data and multidimensional molecular embeddings url: academic.oup.com/bib/article/...

13.02.2026 21:59 ๐Ÿ‘ 4 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Membrane-associated effluxosomes coordinate multi-metal resistance in Mycobacterium tuberculosis - The EMBO Journal Bacterial pathogens must withstand metal-induced stress during infection, yet the mechanisms by which they sense and respond to toxic metal ions remain incompletely understood. Here, we uncover a prev...

๐ŸŽ‰ ๐„๐ฑ๐œ๐ข๐ญ๐ž๐ ๐ญ๐จ ๐ฌ๐ก๐š๐ซ๐ž ๐จ๐ฎ๐ซ ๐ง๐ž๐ฐ ๐ฉ๐ฎ๐›๐ฅ๐ข๐œ๐š๐ญ๐ข๐จ๐ง ๐ข๐ง ๐“๐ก๐ž ๐„๐Œ๐๐Ž ๐‰๐จ๐ฎ๐ซ๐ง๐š๐ฅ!

After 8 months of revision, our work is now online: shorturl.at/WHmFq

We uncover a previously unrecognized way that ๐‘€๐‘ฆ๐‘๐‘œ๐‘๐‘Ž๐‘๐‘ก๐‘’๐‘Ÿ๐‘–๐‘ข๐‘š ๐‘ก๐‘ข๐‘๐‘’๐‘Ÿ๐‘๐‘ข๐‘™๐‘œ๐‘ ๐‘–๐‘  survives toxic metal stress during infection.
...

13.02.2026 15:43 ๐Ÿ‘ 30 ๐Ÿ” 19 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
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๐Ÿšจ New preprint!

Together with @carobarisch.bsky.social lab, we investigated how intracellular compartmentalization shapes lipid acquisition in mycobacteria

Interestingly, deleting one FACL enzyme (FACL6) revealed striking compartment-dependent phenotypes ๐Ÿ”ฌ

Check it out: doi.org/10.64898/202...

12.02.2026 10:30 ๐Ÿ‘ 21 ๐Ÿ” 11 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 3

Beautiful and extensive work from the @carobarisch.bsky.social and @soldatilab.bsky.social labs demonstrating that nutrient utilization in intracellular mycobacteria is dependent on their intracellular location.

Visionary work!!

www.biorxiv.org/content/10.6...

12.02.2026 18:46 ๐Ÿ‘ 8 ๐Ÿ” 2 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Two more weeks to apply - come join us () in The Netherlands as a postdoctoral researcher on large-scale metagenomic exploration of new lineages!

12.02.2026 07:46 ๐Ÿ‘ 17 ๐Ÿ” 27 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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I am super excited that our paper on inter-laboratory comparability of non-targeted LCโ€“MS/MS analysis of dissolved organic matter was just published in ES&T.

pubs.acs.org/doi/10.1021/...

07.02.2026 18:28 ๐Ÿ‘ 15 ๐Ÿ” 5 ๐Ÿ’ฌ 6 ๐Ÿ“Œ 0
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Unveiling Immune System Perturbations in Early Development Through Zebrafish Models of NADHX Repair Deficiency The vital cofactors NADH and NADPH are prone to hydration, forming hydroxylated redox-inactive derivatives (NADHX and NADPHX) in cells. These damaged metabolites are repaired by two highly conserved ...

doi.org/10.1002/jimd...

06.02.2026 07:57 ๐Ÿ‘ 2 ๐Ÿ” 2 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Mapping of the viral shunt across widespread coccolithophore blooms using metabolic biomarkers | PNAS The viral shunt is a fundamental ecosystem process which diverts the flux of organic carbon fixed through photosynthesis during algal bloom events ...

๐ŸŒŠPaper announcement! ๐Ÿ“ฃ
Viral infections rewire the metabolic makeup of their host and thereby create distinct chemical signatures. Can we use metabolic biomarkers to diagnose infections of algal blooms in the ocean?
Well, take a look at our new article led by Conny Kuhlisch in @pnas.org
>>

05.02.2026 17:22 ๐Ÿ‘ 28 ๐Ÿ” 15 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 1
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Two fully funded PhD candidate positions in Electromicrobiology (3 years) Application deadline: 4 March 2026 at 23:59 hours local Danish time

In addition to the 2 postdoc jobs posted yesterday, weโ€™re recruiting 2 PhD students (environmental microbiology/ molecular ecology) to join us from April. The projects will map microbial populations across niches in bioelectrochemical systems relevant to biomethanation & link them to performance.

04.02.2026 16:17 ๐Ÿ‘ 8 ๐Ÿ” 16 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
Cartoon representing the mycobacterial oxidative phosphorylation system, including cytochromes, NDH-2, and ATP synthase. Taken from Figure 1 of the article.

Cartoon representing the mycobacterial oxidative phosphorylation system, including cytochromes, NDH-2, and ATP synthase. Taken from Figure 1 of the article.

#Microbiology

The anti-tuberculosis drug bedaquiline targets the mycobacterial ATP synthase, but how that leads to bacterial death is unclear

Here the authors clarify how bedaquiline works

@jnblab.bsky.social @morwan.me
#TBSky #antibiotics #AMR

http://dlvr.it/TQjZ0W

02.02.2026 17:07 ๐Ÿ‘ 36 ๐Ÿ” 20 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 0