Marco Di Stefano

Looping specificity of Polycomb response elements requires GAF and a combinatorial code of looping factors Chromatin looping between cis -regulatory elements is essential for precise developmental gene expression, and its disruption is frequently linked to disease. Polycomb Response Elements (PREs) are spe...

I found interesting :
-"Surprisingly, PRE looping does not require the PcG subunit Polyhomeotic (PH) or the repressive histone marks H3K27me3". They suggest: Looping specificity of Polycomb response elements requires GAF and a combinatorial code of looping factors.

www.biorxiv.org/content/10.1...