Expansion microscopy improves resolution, but integration with SMLM remains challenging.
In our new preprint, we present a simplified strategy using spontaneously blinking dyes, validated against well-defined reference structures including NPCs and PicoRulers!
➡️ www.biorxiv.org/content/10.6...
Congratulations Arindam and welcome back to Würzburg!
🚨
New Preprint!
Ex-dSTORM resolves fine details of the molecular architecture of CCPs, the 8-nm periodicity of microtubules, and the docking site of synaptic vesicles at the presynapse of hippocampal neurons.
▶️ www.biorxiv.org/content/10.1...
Welcome to the youngSMLMS, a pre-SMLMS event for students, PhDs & PostDocs!
We’ll explore science & career in workshops, talks, roundtables, a panel and with time to network.
--> Thanks to our sponsors, youngSMLMS is free & we cover accommodation for all presenting their work. Thus, register now!
Fully Funded PhD Scholarship in Centrosome Biology in the lab of Prof Ciaran Morrison: www.findaphd.com/phds/project...
Amazing, congratulations!
Look what's happening at the French Embassy in Washington DC.
Chemical Solutions to Structural Biology symposium.
Registration and abstract submission now open:
isbuc.ku.dk/chemical-sol...
An excellent review about fluorescence labeling strategies by @beliulab.bsky.social Gerti Beliu and colleagues from Würzburg University - highly recommended reading for everybody interested in fluorescence microscopy!
🆕 Our new functionalized docetaxel probe enables superior visualization of dense mitotic spindle structures during cell division by expansion microscopy!
▶️ pubs.acs.org/doi/10.1021/...
SAVE THE DATE 👇
#FiNS2025
Frontiers in Neurophotonics Symposium 2025
frontiersneurophotonics.org
#Bordeaux, 6-9 Oct 2025
@iins-bordeaux.bsky.social
@cnrs.bsky.social
@univbordeaux.bsky.social
@neurobordeaux.bsky.social
@cnrsbiologie.bsky.social
@gaellerecher.bsky.social
NIH-supported research saves lives: here are two "poster" human beings to prove it.
Emily Whitehead: cured of her leukemia by CAR-T developed at Penn.
Victoria Gray: major symptoms of her sickle cell disease resolved following CRISPR gene editing - path paved at Boston Childrens, UW, UC Berkeley.
Mode of action of the new microscopy method LLS-TDI-DNA-PAINT. On the top right, the RTX antibody was visualised on a Raij-B cell: it is easy to see how it links the CD20 molecules in the membrane. Bottom right: the hedgehog-shaped appearance of a living Raji B cell after the antibody has bound. The surface protein CD45, which is homogeneously distributed on the cell surface, is also labelled in green. (Image: Arindam Ghosh / University of Würzburg)
Delighted to launch our activities on Bluesky with this great news: Our researchers @sauer-lab.bsky.social show in @science.org, how therapeutic #antibodies interact with B cells – thanks to an innovative method of super-resolution microscopy. Congratulations!
➡️ www.uni-wuerzburg.de/en/news-and-...
🔬 Ever wondered how therapeutic antibodies work?
3D LLS-TDI-DNA-PAINT and live-cell LLS microscopy allow decoding of the molecular interplay of endogenous CD20 on B cells with therapeutic antibodies.
📄 Read more: www.science.org/doi/10.1126/...
Super happy to see the manuscript of my former PhD student and close friend Arindam Ghosh, @arindam92.bsky.social, and the Markus Sauer lab, @sauer-lab.bsky.social, being pblished in Science: www.science.org/doi/10.1126/...
Well-deserved Luke
Happy to see my MSCA project with @jbneuro.bsky.social lab available on @biorxiv-neursci.bsky.social
We Increased network activity in vivo and used dSTORM to look at the nanoscale organization of inhibitory synapses formed onto the AIS and onto tufts dendrites of L2/3 S1 Cortex!
