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Scott Thompson, PhD

@sthom003

Professor of Psychiatry, Univ of Colorado School of Medicine. Director, Psychedelic Public Policy Partnership. Synaptic physiologist studying depression, antidepressant drug actions, and all things psychedelic in mice & people. Link: BaleThompsonLTP.org

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15.11.2024
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Latest posts by Scott Thompson, PhD @sthom003

I am just now catching up on the fact that the FDA was demanding Uniqure do sham brain surgeries (from what I can tell, comprising simulated burr holes and 10-12 hours of anesthesia) in their placebo arm for their Huntington's therapeutic, and I'm absolutely floored that this was a serious demand.

07.03.2026 00:06 πŸ‘ 160 πŸ” 57 πŸ’¬ 9 πŸ“Œ 8

Tried that. This guy’s got a common name.

27.02.2026 21:21 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

As a woman and an academic, why do I feel like I’ve read this story a hundred times - while the names change, the plot is the same. It feels like gut punch every time. We have a long way to go in changing this culture.

27.02.2026 18:57 πŸ‘ 12 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

Agreed!! It also puts us academics in a bind. Example: I am involved with putting together a small meeting paid for by private donors. I know nothing about them. How do I run a criminal background check?

27.02.2026 20:20 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Stimulating the brain with Damien Fair The MacArthur Foundation β€œgenius” discusses his return to his home state of Minnesota and why it’s important to protect the developing brain.

MacArthur Foundation β€œgenius” @drdamienfair.bsky.social discusses his return to his home state of Minnesota and why it’s important to protect the developing brain, in this episode of β€œSynaptic.”

By Brady Huggett

#neuroskyence

www.thetransmitter.org/synaptic/sti...

25.02.2026 21:10 πŸ‘ 21 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

Let’s not forget his co-director. If you’re not a mad scientist, you’re not paying attention.

25.02.2026 18:13 πŸ‘ 6 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Finally - a detailed look at how inputs from the PFC and hippocampus converge in the NAc! Well done!

24.02.2026 16:52 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Have you seen the Trump skating AI video? This is much more realistic.

23.02.2026 22:05 πŸ‘ 14 πŸ” 10 πŸ’¬ 0 πŸ“Œ 0
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On Failure and β€œPathological Persistence” in Science If you look at a CV, academic life can appear very linear. Degrees lead to positions. Grants lead to papers. Papers lead to promotions…

It felt like the right time for a reminder. This is based on an older interview but almost too relevant today. β€œOn Failure and β€œPathological Persistence” in Scienceβ€œ by Michael Yassa on Medium: medium.com/@myassa_6289...

23.02.2026 16:18 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1
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DOJ Removed Record of Multiple FBI Interviews with Underage Trump Accuser, Epstein Data Shows The FBI spoke at least four times with a woman who credibly accused Trump of sexually assaulting her when she was a minor, Epstein files show. That document is no longer accessible on the DOJ website.

substack.com/home/post/p-...

21.02.2026 21:56 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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N,N-dimethyltryptamine (DMT) is neither formed nor retained in serotonin terminals in the rat brain Mammalian brain may contain an endogenous pool of the psychedelic substance N,N-dimethyltryptamine (DMT), which may act as a co-transmitter with serot…

We were trying to confirm the precens of DMT in the brain and in particularly in serotonin neurons.

But to our surprice, DMT is neither in the brain or taken up by serotonin nerve terminals!

www.sciencedirect.com/science/arti...

17.02.2026 15:19 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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#donaldtrump

12.02.2026 21:07 πŸ‘ 4523 πŸ” 892 πŸ’¬ 139 πŸ“Œ 71

Welcome!

11.02.2026 00:25 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Prediction: Kidnapped President Madura confesses to election interference in exchange for a DOJ plea deal that sets him up in the Club Fed prison next to Ghislaine Maxwell. Trump uses it as pretext to nationalize elections and the Roberts court says OK because we can’t second guess national security

05.02.2026 20:07 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Sir Ian McKellen performing a monologue from Shakespeare’s Sir Thomas More on the Stephen Colbert show. Never have I heard this monologue performed with such a keen sense of prescience. Nor have I ever been in this exact historical moment.TY Sir Ian, for reaching us once again.
#Pinks #ProudBlue

05.02.2026 11:50 πŸ‘ 32284 πŸ” 13859 πŸ’¬ 589 πŸ“Œ 1595

You’re right! It’s way smaller!

30.01.2026 02:43 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Another day, another failure of AG Pam Biondi to comply with the law. This time, holding back promising research on cannabis and psychedelics by refusing to bring Nixon’s archaic war-on-drugs regulations into the 21st century.

I guess she’s too busy redacting Trump’s name from the Epstein files.

28.01.2026 16:35 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

As a MN girl, I am sickened by what is happening in my home state. Please call your members of Congress and tell them that the DHS spending bill must prohibit ICE and Border Patrol agents from carrying guns and that agents do not have absolute immunity under the law if they harm civilians. Now. β˜ŽοΈπŸ“’

16.01.2026 20:14 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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When Everything Changes at Once: Making Sense of Institutional Overload NIH Office of Extramural Research is Implementing a Plan for β€œAdministrative Burden Reduction”

Latest post from Dr. Ginexi on NOFO guidance, "reductions in burden," and subsequent confusion at #NIH.

14.01.2026 15:15 πŸ‘ 25 πŸ” 15 πŸ’¬ 0 πŸ“Œ 2
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13.01.2026 14:29 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thank you to all the courageous panelists at today’s lived experience panel at #ACNP2926 and thank you to @acnporg.bsky.social for bringing these vital voices to the conversation. Their hard-earned insights can help us all do better, more impactful, more meaningful science!

13.01.2026 14:29 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Thank you ACNP for having the meeting at the Atlantis! Trying a new way to fund the lab - better odds than the NIH!

10.01.2026 00:49 πŸ‘ 17 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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SHAME ON YOU DELTA AIRLINES!!! COWARDS!

09.01.2026 21:45 πŸ‘ 7 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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IBRO announces the Scientific Program Committee for the 2027 World Congress Following a rigorous global selection process led by co-chairs Dr. Sheena Josselyn and Dr. Thiruma V. Arumugam, who aimed at establishing a scientifically broad Scientific Program Committee (SPC) for…

Excited to be working with colleagues around the world (including @drjkhokhar.bsky.social @jojolab.bsky.social and CHAIR @sjo09.bsky.social) on the @ibroorg.bsky.social World Congress in Cape Town, 2027! ibro.org/ibro-announc...

18.12.2025 22:22 πŸ‘ 27 πŸ” 4 πŸ’¬ 1 πŸ“Œ 1

Add HHS to the DoD for agencies committing murder in our names.

17.12.2025 18:50 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
A black-and-white photo shows Dr. Leila Denmark (center), an elderly woman with glasses, seated and smiling while looking at a baby who is laughing and facing her. Another younger woman is also seated to the right, laughing and placing her hand near the baby's midsection. The scene suggests a warm, inter-generational interaction, possibly in a clinical or home setting. Dr. Denmark was a pioneering pediatrician, known as the world's oldest practicing pediatrician upon her retirement at age 103.

A black-and-white photo shows Dr. Leila Denmark (center), an elderly woman with glasses, seated and smiling while looking at a baby who is laughing and facing her. Another younger woman is also seated to the right, laughing and placing her hand near the baby's midsection. The scene suggests a warm, inter-generational interaction, possibly in a clinical or home setting. Dr. Denmark was a pioneering pediatrician, known as the world's oldest practicing pediatrician upon her retirement at age 103.

Dr. Leila Denmark co-developed the pertussis (whooping cough) vaccine.

World's oldest practicing pediatrician until she retired at age 103 (after 73 yrs). At the time of her death at age 114 & 60 days, she was the 5th-oldest validated living person in the world & 3rd-oldest in the US. #WomenInSTEM

15.12.2025 15:35 πŸ‘ 2894 πŸ” 682 πŸ’¬ 38 πŸ“Œ 24
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07.12.2025 20:15 πŸ‘ 912 πŸ” 279 πŸ’¬ 4 πŸ“Œ 13

What is the source of this idiocy?

07.12.2025 04:22 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Absolutely insane paragraph

07.12.2025 02:49 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 2

Damn right!

04.12.2025 22:31 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0