Guillaume Dorothée

Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease - Nature The immune-checkpoint molecule TIM-3 regulates microglial homeostasis, and its microglial-specific deletion reduced cognitive impairment in a mouse model of Alzheimer’s disease.

www.nature.com/articles/s41...

JCI - A single-cell compendium of human cerebrospinal fluid identifies disease-associated immune cell populations

A single-cell compendium of human cerebrospinal fluid identifies disease-associated #immune cell populations
#neuroskyence
#compneurosky
www.jci.org/articles/vie...

Demyelination-derived lysophosphatidylserine promotes microglial dysfunction and neuropathology in a mouse model of Alzheimer’s disease
www.nature.com/articles/s41...