Carmelo Ferrai

Join us tomorrow for two exciting enhancer talks!

Self-clustering of three CBX2 molecules drives PRC2 to promote facultative heterochromatinization of Polycomb target genes Ingersoll et al. uncover that approximately three CBX2 molecules drive PRC2 clustering and H3K27me3 deposition in mESCs. This process supports a model in which few CBX2 molecules self-cluster on chrom...

Self-clustering of three CBX2 molecules drives PRC2 to promote facultative heterochromatinization of Polycomb target genes

www.cell.com/molecular-ce...

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Not much time left... but still!
Please share/circulate or apply!

Thanks a lot @lizebonaaugust.bsky.social
Happy that you liked it!

Wow!

Mechanobiology of the Extracellular Matrix This Collection aims to highlight fundamental and translational advances in ECM mechanobiology.

🔔🧪 Call for Papers – #Mechanobiology of the #ExtracellularMatrix 🧬🛠️

Excited to serve as Guest Editor — together with Jacopo di Russo and Jennifer Young — of a new 𝐧𝐩𝐣 𝐁𝐢𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐏𝐡𝐲𝐬𝐢𝐜𝐬 𝐚𝐧𝐝 𝐌𝐞𝐜𝐡𝐚𝐧𝐢𝐜𝐬 Collection on “Mechanobiology of the ECM”.

Deadline: 14 May 2026!

www.nature.com/collections/...

Very nice!

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Reminder that I will be speaking this Wednesday about my postdoc work. You have been warned. 🧪

Thanks!

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NELF prevents transcriptional readthrough into DNA replication zones in cancer cells - EMBO Reports Regulation of RNA polymerase II (Pol II) transcription is closely associated with cell proliferation. However, it remains unclear how the Pol II transcription program is rewired in cancer to promote u...

NELF prevents transcriptional readthrough into DNA replication zones in cancer cells

link.springer.com/article/10.1...

You still have 3 days to apply to the postdoc positions available in my lab 😀
🔬Come and work with us 🔬

Hey Chromatin Friends!
Long time no chromatin question...
For many of you, CUT&x (RUN/Tag) works really well but some of you have had their frustrations with CUT and "gone back" to ChIP-Seq. Can you share your experiences in the comments!?
Would love to hear from you!
Sharing is appreciated : )

Thanks a lot!

Hey Simon, thank you instead. It was great working together!

Just saying: if you have the F'ing Nobel Prize and publish every few months in Science or Nature, include the first author as co-corresponding author....

Preprint alert! 🥸

Yajie Zhu (PhD graduate) and Mariano Barbieri (postdoc, @spp2202.bsky.social Accelerator award) produced a package that will classify loops in your #3Dgenomics data based on (whichever) epigenomic data you have available. Keep reading...

1/n

www.biorxiv.org/content/10.6...

Thanks a lot! 👋🏽

Thanks Mariano!!!!

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Thanks Mark! What a great summary comment! Love it!!! 😍

Postdoc Research Group Schur The Schur lab at the Institute of Science and Technology Austria (ISTA) has an open postdoc position for a highly motivated candidate to be part of our ERC-funded project ActinID. Our Group ...

Open Postdoc position in our lab!
#actin #Huntingtin #cryoET #cellbio
If you enjoy working at the interface of cell biology, structural biology, and quantitative imaging, this could be an excellent fit.

ista.ac.at/en/job/postd...

Please share and feel free to reach out if there are questions!

Thanks Miriam!
I am happy that the story is out!
We made some progress since the last time we met!
Glad you liked it!
All the best!
A si biri!

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Thanks Lennart! Glad you like it!

Tread -1- EpiSci - 🧬 - 🧪 I am very proud to share with you our new study that you can access on @biorxivpreprint.bsky.social (see link below)
"The Interaction with Nanotopographical Environment regulates nuclear mechanoresponse in mESCs via Histone Demethylase KDM3A.
www.biorxiv.org/content/10.6...

Tread -11- @akispapantonis.bsky.social @carstenschulte4.bsky.social

We hope that you will like our study! Reach me out for discussions and feedback!