Orientierung für Fachärzt:innen, praxisnah durch Fallberichte & Austausch mit Christine Moissl-Eichinger @chmoei.bsky.social, CoE Key Researchers Gregor Gorkiewicz @gregorkiewicz.bsky.social und Alexander Moschen u.a.
Come join us! Soon I will be advertising a postdoc vacancy in my group as part of my @erc.europa.eu AdG project 'DARK ROOTS'. Focus of the project will be on phylo- and metagenomic mining of novel prokaryotic lineages. I will soon post a link here - stay tuned, and please repost! #asgardarchaea
Proud PI: Austrian microbiome research award for my PhD student Charlotte Neumann! Thanks @microbesplanet.bsky.social
Out in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...
Happy to share that our story on the bacterial archaellum was published today in @natmicrobiol.nature.com
www.nature.com/articles/s41...
Congrats to the authors: @sshamphavi.bsky.social @loumollat.bsky.social @mariejoest.bsky.social Najwa Taib and @sgribaldo.bsky.social
This study was led by my amazing PhD student @theeonflux.bsky.social and @chriku.bsky.social with great collaborators + support from @fwf-at.bsky.social and RESPImmun @medunigraz.at
🚨 New preprint!
We built the largest respiratory pan-microbiome atlas yet >4,000 metagenomes from nose to lung.
👉 In health: a connected microbial continuum
👉 In disease: this structure collapses
#microbiome #microsky
Read: www.biorxiv.org/content/10.1...
🚨 Imagine a bacterium that refuses to follow the textbook:
It grows as tangled filaments, divides unevenly, reshapes its own membranes… and even builds grappling hooks.
Meet Litorilinea aerophila — and here’s why it blew our minds.
Ein Screenshot eines Mobiltelefons
Neues aus der Mikrobiom-Forschung!
Archaeen – kaum bekannte Mitbewohner in unserem Darm – senden winzige Bläschen, um mit ihrer Umwelt zu kommunizieren.
Ein Team der Med Uni Graz hat das jetzt erstmals detailliert beschrieben. Veröffentlicht in Nature Communications ➡️ https://bit.ly/47gnl9R.
Here you will find all details on the project and how to apply. Please apply only through this webpage (emails cannot be considered): www.medunigraz.at/en/doctoral-... (our project is listed on page 22 in "Projects")
🚨 2 funded #PhD positions (ERC Adv Grant) in the Moissl-Eichinger Lab, Graz! Study Methanobrevibacter as a keystone in the gut microbiome.
💡 Omics, modeling, synthetic consortia
📅 Deadline: Sept 10, 2025
🌍 Int’l applicants welcome!
Application link below.
#microbiomesky #archaeasky #microsky
Wow, congrats Simo!!! Well deserved!!!
Congratulations to all winners - and "happy World Microbiome Day"!!
So grateful. Let’s dive deeper into the archaeome!!
This is not a solo achievement. It’s the result of years of support, teamwork (cudos to the amazing MEL TEAM), and inspiring collaborations. Huge thanks to my incredible team, the @medunigraz.at environment, and all our partners.
Some big news: I’ve been awarded an ERC Advanced Grant to further explore the roles of #archaea in gut #microbiomes and beyond.
@erc.europa.eu
#ERCAdG #ARCHMETH #Microbiome #Archaea #sciencepassion
Klimaschutz trifft Darmgesundheit: Unsere Mikrobiomexpertin Christine Moissl-Eichinger erhält den prestigeträchtigen Advanced Grant (2,5 Mio. €) des für ihre Forschung zu Methanobrevibacter – einem winzigen Mikroorganismus mit großem Potenzial ➡ https://bit.ly/3FDDJpO.
#ERCAdG
New @fwf-at.bsky.social CoE Microplanet Publication in NatureComms! @theviktoriaeffect.bsky.social from the lab of @chmoei.bsky.social @medunigraz.at profiled the proteome & metabolome of extracellular vesicles from key gut archaea, revealed immune-stimulating capacities and unique molecular cargo.
Proud to share this collaborative effort—thank you to the entire team @, to @medunigraz.at, all our collaborators and their teams + @microbesplanet.bsky.social, and of course @fwf-at.bsky.social for financial support!
This work sheds light on the trophic control Archaea may exert over the cancer microbiome, urging us to rethink their role in health and disease.
🔍 Using metabolic modeling, co-culture assays, and metabolomics, we show that:
• M. smithii forms mutualistic interactions with CRC-associated bacteria like Fusobacterium nucleatum
• It enhances bacterial growth and metabolite production
• It produces tumor-modulating archaeal metabolites
In this study, amazing @roxymzh.bsky.social screened over 1,800 metagenomes from 19 clinical cohorts and found that Methanobrevibacter smithii—the dominant gut archaeon—is consistently enriched in colorectal cancer (CRC) patients.
🚨 New preprint alert!
We report what might be the first mechanistic link between gut Archaea and human disease.
Methanobrevibacter smithii is enriched in CRC patients—and boosts growth of cancer-associated bacteria like F. nucleatum.
www.biorxiv.org/content/10.1...
@archaeasky @microbiomesky
Maybe next time! 😉 More archaea work coming up! 😃
What a missed opportunity... 🤔 We should have declared an official "Archaeal Week" at Nature Communications! 😆
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
#Archaea #ArchaeaSky 🦠
Special thanks goes to the amazing SFB immunometabolism, which made this work possible, and of course the extraordinary, phantastic MEL team.
Supported by @microbesplanet.bsky.social
@medunigraz.at @fwf-at.bsky.social - Thank you!
Together, these papers open new doors into previously unseen archaeal communication towards host and host microbiome
#archaeasky #microbiomesky
#Archaea #Microbiome #ExtracellularVesicles #GutHealth #Science #NatureCommunications #MicrobialEcology #Methanogens #MultiOmics
