Catalina Vasilescu, PhD

📢Last weeks #immunometabolism discoveries @biomednews.bsky.social ⬇️⬇️⬇️

biomed.news/bims-imicid/...

Interesting finding:

The glycolytic metabolite phosphoenolpyruvate restricts cGAS-driven inflammation to promote healthy aging.

Vitamin B2 and B3 nutrigenomics reveals a therapy for NAXD disease A nutrigenomics framework identifies genetic diseases amenable to vitamin B2 and B3 therapies. This approach nominates vitamin B3 as a therapy for NAXD deficiency, a lethal neurodevelopmental disorder...

Last 2 weeks of literature on #Mitochondria in #Health & #Disease! 🤍 💚
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biomed.news/bims-mitdis/...

@biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social

Vit B2 and B3 nutrigenomics reveals a therapy for NAXD disease
www.cell.com/cell/fulltex...

Functional nutrient-genetic profiling reveals biotin and FBXW7 are essential to bypass glutamine addiction Lisci et al. present a unified model revealing how cells escape glutamine addiction, a metabolic vulnerability of several cancers. Combining systematic genetic and nutrient screens, they show that bio...

Our story on #FBXW7 and #biotin in #glutamine_addiction is now peer-reviewed and published in Molecular Cell! Heroic work led by the very first postdoc of the lab @miriamlisci.bsky.social. Have a look!

www.cell.com/molecular-ce...

Figure 9: Anti-influenza mechanism of action of cis-aco. DOI: 10.1038/s44321-026-00379-8.

📢Last weeks #immunometabolism discoveries 🧪@Bims_BiomedNews ⬇️⬇️⬇️

biomed.news/bims-imicid/...

Interesting finding:

Cis-aconitate therapy protects against influenza mortality by dual targeting of viral polymerase and ERK/AKT/NF-κB signaling #mitochondria #metabolites

A genetically encoded bifunctional enzyme mitigates redox imbalance and lipotoxicity - Nature Metabolism The authors present a genetically encoded tool based on a bifunctional enzyme that can regenerate NAD+ while executing an engineered glycerol shunt. The tool successfully restored redox imbalance and ...

A wonderful collection of literature from #week8 on #Mitochondria in #Health & #Disease! 📚

biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social

A [...] bifunctional enzyme mitigates redox imbalance and lipotoxicity
www.nature.com/articles/s42...

Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species - Nature Metabolism Boosting mitochondrial metabolism in neurons in central memory circuits by enhancing Ca2+ retention in the mitochondrial matrix is shown to improve long-term memory formation in flies and mice.

Most recent collection of papers on #Mitochondria in #Health and #Disease!
#week7 #MitochondrialDisease 📚
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social
www.nature.com/articles/s42...

Sub-second volumetric 3D printing by synthesis of holographic light fields - Nature A new method is described that uses a periscope to generate high-speed, high-resolution projections of light fields, enabling sub-second volumetric 3D printing of millimetre-scale objects without rota...

Latest issue of curated #engineeredlivingmaterials feed:
biomed.news/bims-enlima/...

via @biomednews.bsky.social #livingmaterials #ELMs

includes research on: sub-second volumetric 3D printing, fluorescently labeled gradient hydrogels, learning nature's assembly language with polymers & more 🧪

Good morning! this week's selection of articles and #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/...
Highlight: Mechanisms linking cytoplasmic decay of translation-defective mRNA to transcriptional adaptation www.science.org/doi/10.1126/...

Good morning, all! Here is a beautiful selection of papers in #cancermetabolism and #mitochondrialbiology. Don't miss it! biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading

"For everything you do, there will be a last time that you do it."-William B. Irvine

Mechanisms and disease relevance of mitochondrial translation in humans Nature Reviews Molecular Cell Biology, Published online: 13 February 2026; doi:10.1038/s41580-026-00948-2This Review discusses new insights into the intricate regulation of mitochondrial protein synthesis, the pathological consequences of its dysfunction in cancer and immunity, and the complexity of therapeutic targeting of mitochondrial translation.

New Online! Mechanisms and disease relevance of mitochondrial translation in humans

Let’s celebrate women and girls in scientific research! Often underestimated, women drive research in biomedical sciences both intellectually and at the bench. Research should be a “gender-blind” endeavor, but rarely is. Stop bigotry ! Stop unconscious bias ! Go women & girls!

Advancing gender equality in STEM education: Inspiring girls to pursue Women and girls remain underrepresented in science, technology, engineering and mathematics (STEM), often due to persistent stereotypes and limited access to opportunities. Through education

Today is International Day of Girls and Women in Science. UNESCO show that women represent only 35% of STEM graduates around the world. We must stop losing so much talent that could improve the world for all www.unesco.org/en/articles/...

Chrysanthi Moschandrea and I have developed a new conceptual framework for understanding the role of metabolism in cancer, which we term metabolic permissiveness. We are eager to hear your thoughts on this topic.

genesdev.cshlp.org/content/earl...

Mitochondrial superoxide regulates nuclear envelope integrity and ageing via redox-mediated lipid metabolism - Nature Metabolism Mitochondrial superoxide production is shown to preserve nuclear envelope integrity by controlling lipid peroxidation, with impact on nuclear and organismal ageing in C. elegans.

A new collection of papers on #Mitochondria in #Health and #Disease! #MitochondrialDisease 📚
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mt superoxide regulates nuclear integrity and ageing via lipid metab

www.nature.com/articles/s42...

So pretty! What's happening with the DNA there? Or should we wait for the publication? 😀

Quick recovery! 🙌

A new collection of papers from #week5 on Mitochondria in Health & Disease! #MitochondrialDisease
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social

Among highlights
www.nature.com/articles/s41...

A unifying theory of #ageing from colleagues at #NewcastleUni 👇🏼👇🏼👇🏼

Would be interesting to hear your feedback in comments, could this be a new framework for the field of #biogerontology?

www.biorxiv.org/content/10.6...

Happy Sunday egg-ficionados! Here comes your weekly issue of #cebooc:

biomed.news/bims-cebooc/...

Highlight: pubmed.ncbi.nlm.nih.gov/41606324/ by @brugueslab.bsky.social

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A new collection of papers from #week5 on Mitochondria in Health & Disease! #MitochondrialDisease
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social

Among highlights
www.nature.com/articles/s41...

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#Autophagy and #mTOR papers from last week, thanks to @biomednews.bsky.social for running a reliable search engine keeping us up to date with relevant literature. Subscribe to their free services and you won’t regret it!

biomed.news/bims-auttor/...

Good Sunday, mitolovers. Here is the weekly curated issue of papers in #cancermetabolism and #mitochondrialbiology, with truly remarkable papers: lnkd.in/e7HDuVuU @biomednews.bsky.social #keepreading

"Attention is the rarest and purest form of generosity."-Simone Weil

Good Morning! This week's selection of articles on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/...
Highlight: CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis www.cell.com/cell/fulltex...

Artificial Symbiosis for Bulk Production of Bacterial Cellulose Composites Co-cultivation of the cellulose-producing bacterium with the microalga enables bulk formation of bacterial cellulose under static incubation, with photosynthetically active oxygen-generating sites th...

Latest issue of curated #engineeredlivingmaterials feed:
biomed.news/bims-enlima/...

via @biomednews.bsky.social #livingmaterials #ELMs

includes research on: bacterial cellulose composites (h/t @proftomellis.bsky.social, @vignolinilab.bsky.social), living bioelectronics devices, & more 🧪

Light-Responsive Protein Hydrogels Bridge Molecular Mechanics and Frequency-Dependent Mechanotransduction Dynamic extracellular matrix mechanics regulate fundamental cellular processes, yet precise control over spatiotemporal rigidity modulation remains challenging. Protein-based photoresponsive hydrogels...

Latest issue of curated #engineeredlivingmaterials feed:

biomed.news/bims-enlima/...

via @biomednews.bsky.social #livingmaterials #ELMs

includes research on: remote controlled proteins, volumetric bioprinting, light-responsive protein hydrogels, biocatalytic surfaces in architecture, & more 🧪

https://academic.oup.com/nar/article/54/2/gkag008/8433879?login=false

A new collection of papers on Mitochondria in Health and Disease! #week3 #MitochondrialDisorders
biomed.news/bims-mitdis/...

@biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social

Human mitochondrial helicase Twinkle has RNA binding, annealing, and strand-exchange activities

Happy Sunday! No matter if you are enjoying a lazy Sunday or an active one, don't miss the latest issue of #cebooc here:

biomed.news/bims-cebooc/...

Highlights: pubmed.ncbi.nlm.nih.gov/41565805/ and pubmed.ncbi.nlm.nih.gov/41570148/

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Good Sunday, all. Here is the weekly curated summary of papers in #cancermetabolsim and #mitochondrialbiology. Don't miss it! lnkd.in/e9QJz9AZ @biomednews.bsky.social #keepreading

"Start right now. Take a small step you can call your own. Don't follow someone else's heroics."-David Whyte

Good morning! This week's selection of articles and #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/...
Highlight: Multimodal supramolecular targeting chimeras enable spatiotemporally resolved protein degradation in vivo www.cell.com/cell/abstrac...

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Another strong week for analytical chemistry. Here is the latest issue of bims-metlip covering analytical and computational methods for metabolomics and lipidomics analysis

biomed.news/bims-metlip/...

A collaboration with @biomednews.bsky.social