Bryan White, PharmD, FIDSA, BCIDP

Totally agree. Trainees have a bunch of energy/enthusiasm. They often overcommit themselves to things. Having mentors advise on what to say no to is important.

Excited to hear more details about the SNAP and CloCeBa trials for MSSA bacteremia being presented at ESCMID this afternoon. Looks like a win for team cefazolin. It will be practice changing with the current variations in practice for treating MSSA BSI. #ESCMID

It builds on a previous paper by Crass and Pai which derived an equation for vancomycin AUC dosing in obese patients. academic.oup.com/ofid/advance...

Our new paper on vancomycin AUC dosing in obesity is out. It showed decreased AKI in obese patients using AUC dosing as compared to trough dosing. Rates of AKI were lower in the AUC group compared to the trough group (11.3% versus 25.2%, p<0.001). This work was led by Corey Guidry .

The PGY2 in ID at OU didn’t match and is going into phase 2. Please help spread the word! pharmacy.ouhsc.edu/programs/res...

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Experience with Liposomal Amphotericin B in Outpatient Parenteral Antimicrobial Therapy - PubMed Outpatient parenteral antimicrobial therapy (OPAT) is a safe, effective, and convenient treatment strategy for patients receiving intravenous antimicrobials in the outpatient setting; however, data ar...

It can be done but readmission and complication rates are high. pubmed.ncbi.nlm.nih.gov/33846129/

Excited to launch new tracks in our 2-year ID fellowship program @ou.edu starting July 2025: TxID, Hospital epi/healthcare admin, Trop Med/Global Health, ID/Crit Care.
Tracks come with option for 12-credit certificates, covered by the program:

medicine.ouhsc.edu/academic-dep...

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#IDSky #TxID

Yeah, we just two level trapezoidal pk. It really improved target attainment and AKI in our obese patients. We have a paper under review with our results.

Has anyone been using dalba as 12 weeks of treatment for PJI as per Daptio? Any recs or papers on this would be helpful. #IDsky

Kinda of a crazy night. Went out for ice cream and ran into Oklahoma’s US senator, James Lankford. Talked for 2 minutes about RFK. Nice conversation with a thoughtful politician. #IDsky

PLEASE SHARE WIDELY #medsky #IDsky #obgynsky #pedsky
CDC STI treatment guidelines have been taken down. They are archived here 👇
web.archive.org/web/20250131...

Association of daily body temperature, white blood cell count, and C-reactive protein with mortality and persistent bacteremia in patients with Staphylococcus aureus bacteremia: a post-hoc analysis of... AbstractIntroduction. Classification of patients with Staphylococcus aureus bacteremia (SAB) as complicated versus uncomplicated is based on a combination

Post-hoc analysis of 📷 📷 study in MSSA/MRSA bacteremia:

Persistent fever = indicator for complicated infection

Fever on Day 4️⃣: aOR (3.7 (95% CI: 1.58-8.67)) mortality
Fever on Day 7️⃣: aOR: (8.78 (95% CI: 2.78-27.7)

🚫 assn between ⬆️CRP/WBC and mortality

#IDSky

academic.oup.com/ofid/advance...

Yeah, that would be a bargain. I’ve dropped some of them over the years. They aren’t cheap.

There is a director of pharmacy position open at Bartlett Regional Hospital in Juneau, Alaska. Oversees ~25 rx employees in a 55 bed hospital in Alaska's capital and largest town in Southeast Alaska. I work there several times a year, happy to answer any questions. Spread far and wide!

I don’t. My Merck contacts didn’t know.

This time of the year is exciting as a RPD to review the packets from great candidates who are excited to learn more. #pharmsky

I could go either way. I’d maybe offer a fellows project and see if they liked it.

Yeah there is a paper or two on this topic that are currently under review.

Clinical considerations for oral beta-lactams as step-down therapy for Enterobacteriaceae bloodstream infections - PubMed Clinical considerations for oral beta-lactams as step-down therapy for Enterobacteriaceae bloodstream infections

I do QID. Better exposures based on this study. pubmed.ncbi.nlm.nih.gov/30908107/

I laugh loudly to movies on planes too frequently.

Pharmacy fun fact! You need to be very careful when handling metronidazole. It’s flagyl #medsky #pharmsky

They pushed the dates back for this year, but yeah the format could be updated.

Impact of Obesity in Patients with Candida Bloodstream Infections: A Retrospective Cohort Study - PubMed Worse clinical outcomes were observed for obese versus non-obese patients. Further clinical research is warranted.

Yeah, we dose adjust up all the time. Obese patients do worse (pubmed.ncbi.nlm.nih.gov/32062851/) with candidemia. Obese patients have lower exposures than normal weight patients (pubmed.ncbi.nlm.nih.gov/37272474/). There hasn’t been data that I’m aware of showing improved outcomes with higher doses

I liked lake george NY.

Risk factors for positive follow-up blood cultures in critically ill adults with Gram-negative bacteraemia AbstractObjectives. To evaluate the utility of follow-up blood cultures (FUBCs) for Gram-negative bloodstream infection (BSI) in ICU patients and identify

A retrospective cohort study of Gram-negative BSIs in ICU shows fever, lack of source control and time to repeat follow-up blood culture (FUBC) as risk factors for repeat positive FUBC:
https://doi.org/10.1093/jacamr/dlae144
#JACAMRNews @bryanpwhite.bsky.social

If valve cultures are negative, then I’d go by clearance of blood cultures. If valve cultures are positive, I’d restart the clock.

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UPMC Western Maryland is looking for a full time stewardship pharmacist. Come work with a truly amazing local team and have system support from Tina Khadem, myself, and ~40 other pharmacists! (also - no holidays, no weekends!)

#idsky #amssky #pharmsky #medsky

sidp.mcjobboard.net/jobs/173869