Timothy Bredy

There is something to be said about the massive increase in postdoc applicants for ARC DPs and Ideas grants in the NHMRC. It’s exponentially harder form them given they are competing with seasoned group leaders. The system is in real trouble.

Gold!

The selfish ribosome The ribosome is responsible for protein synthesis in all cells, and is the largest energy consumer in the cell. We propose that the ribosome originated as a mutualistic symbiont of an RNA-dependent RN...

arxiv.org/abs/2602.23268

Like!

I hear you. Awhile back I had the not so bright idea to perform targeted rna sequencing on the bdnf locus. It scared everybody in the lab so much that we had to shelf the project.

@martinowk.bsky.social are you circling back to this monster?

Probably safe to assume ~30% for each panel so cut off for BSB for example, around 355.

Any idea about the success rate for each panel, or the cut off for each?

Two codes of RNA editing by deamination in human diseases - Experimental & Molecular Medicine RNA editing is a process that changes the genetic information in RNA molecules after they are made from DNA. The study explores two main types of RNA editing: adenosine-to-inosine (A-to-I) and cytidin...

like!

www.nature.com/articles/s12...

Colleagues. I’m super excited about presenting at the Canadian 🇨🇦 Neuroscience meeting in May! How’s going and who wants to get together for a catch up?
@canacn.bsky.social

can-acn.org/meeting-2026/

Alright people, re-upping this on your feed. Space is limited so please register soon!

www.neurosas.org/advanced-cou...

Medical Research Matters

Friends and colleagues, please sign this petition to increase the MRFF allocation

Here’s awesome bit of technical work by PhD student Josh Davies in Paul Marshall’s lab at ANU. Proud to part of it. Sex differences run deep when you look at the brain with high resolution.

Excited to share our latest preprint: "SWARM: A Single-Molecule Workflow for High-Precision Profiling of RNA Modifications" www.biorxiv.org/content/10.6...
Led by Stefan Prodic #RNA #Epitranscriptomics #Nanopore 1/6

Another outstanding RNA meeting!

Why emotion research is stuck—and how to move it forward Studying how organisms infer indirect threats and understand changing contexts can establish a common framework that bridges species and levels of analysis.

My perspective in @thetransmitter.bsky.social on why emotion research feels stuck and how we might move forward—by focusing on how the brain uses internal brain models to shape emotional processing across species. www.thetransmitter.org/emotion/why-...

Tom Cech to Davos: RNA research is 'still a big deal' The Nobel laureate and CU Boulder professor, recently ranked #1 globally for RNA research, will speak at the World Economic Forum annual meeting in Davos,

www.colorado.edu/today/2026/0...

We are looking for a postdoc to work on mechanisms of #RNA decay in cancer using #cryoEM with #nanobodies and #minibinders! Please RT

I agree!

"Proteins are just the poor errand boy for RNA".

🧪 Interested in a Cutting-Edge Molecular Neuroscience Meeting at a dream location?

Join us at the EMBO | COB Workshop on Axonal degeneration and regeneration, 18 – 22 October 2026, Onna-son, Okinawa, Japan

meetings.embo.org/event/26-axo...

Here we go! 2026. the year I learn python and do my own dRNA analysis. Digging deep and glad to know @martinalexsmith.bsky.social, @michaelbclark.bsky.social, and all the other nanopore gurus in australia. @nanoporetech.com

This is a great read. Once again, RNA for the win.

Yet another fantastic discovery surrounding cell surface RNAs and cellular function. Congrats @raflynn5.bsky.social and colleagues!

Outstanding! Congratulations Keri!

RNASky! Wow this looks like a great opportunity to learn alot about RNA in the brain......

Alright people, re-upping this on your feed. Space is limited so please register soon!

www.neurosas.org/advanced-cou...

Check out our new manuscript describing the circuit-specific impact of 16p11.2, a chromosomal region linked to neurodevelopmental disorders! @UIowaNeuro @IowaNeuroPharm @Hawk_IDDRC
www.nature.com/articles/s41...

Are there different Arc variants that would drive a permissive local effect on memory vs the intercellular viral response?

How do we reconcile the beneficial role of Arc in memory? Optimal expression range for one role vs the other?

Phosphorylated tau exhibits antimicrobial activity capable of neutralizing herpes simplex virus 1 infectivity in human neurons - Nature Neuroscience The authors found that the Alzheimer’s disease-associated protein tau, widely considered pathogenic when hyperphosphorylated, has a natural function as part of the innate immune system in the brain an...

@jasonsynaptic.bsky.social given the relationship between ARC and HSV-1, interesting finding, n'est-ce pas?

www.nature.com/articles/s41...

Vaults are incredibly interesting ribonucleoprotein complexes that are vital for cellular function.