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Somerset Wu

@somerchem

@University of Sydney / @UC Berkeley Working on serial femtosecond crystallography Genderqueer ๐Ÿณ๏ธโ€๐ŸŒˆ (They/He)

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14.11.2024
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Latest posts by Somerset Wu @somerchem

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A global survey of taxa-metabolic associations across mouse microbiome communities Yilmaz et al. provide a global atlas of murine microbiota and their species variants across many vivaria and wild colonies. By integrating strain-resolved metagenomics, metabolomics, and structural an...

Weekend read:
Global survey of mouse microbiomesโ€”a path to strengthening collaborative science

Searchable resource of microbiome composition variability across numerous murine vivaria & wild mouse colonies w/ insights on taxa-metabolic associations.
www.cell.com/cell-host-mi...

27.02.2026 20:26 ๐Ÿ‘ 6 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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The paradox of immune systems conservation between prokaryotes and eukaryotes Nature Reviews Microbiology, Published online: 05 February 2026; doi:10.1038/s41579-026-01284-0The widespread prokaryotic immune systems, in particular restrictionโ€“modification, CRISPRโ€“Cas and defensive toxinโ€“antitoxin systems, are absent in eukaryotes, whereas relatively rare ones, such as Argonautes and antiviral STAND NTPases, became central to eukaryotic innate immunity. In this Comment, we hypothesize that the cause of this paradox is the drastic reduction of horizontal gene transfer rate in eukaryotes.

New online! The paradox of immune systems conservation between prokaryotes and eukaryotes

06.02.2026 09:47 ๐Ÿ‘ 18 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Adsorptionโ€“microbial integration pioneers sustainable phosphorus cycle - Nature Water Escalating phosphorus pollution and depleting reserves necessitate sustainable control and recovery strategies. Here the authors develop a microbially enhanced Laโ€“Zr-loaded basalt system that achieves...

A new Article in Nature Water by Tianming Wu and colleagues introduces a microbially enhanced Laโ€“Zr-loaded basalt system, achieving over 90% phosphorus removal and recovery. www.nature.com/articles/s44...

03.02.2026 21:55 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Modeling human embryo implantation in vitro Building an in vitro model of receptive endometrium allows investigation of human embryo implantation and early post-implantation development and recapitulates the earliest stages in establishing the ...

An in vitro platform for studying human embryo implantation. This looks like it could be a pretty big deal, if indeed it's a good model.
www.cell.com/cell/fulltex...?

08.01.2026 18:22 ๐Ÿ‘ 14 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
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Walz: "Do you have no decency? We have someone dead in their car for no reason whatsoever. I don't want to be right about this, but I said if they do this they're gonna create a chaotic situation where someone innocent is gonna get killed. And they did it."

07.01.2026 21:19 ๐Ÿ‘ 19712 ๐Ÿ” 5928 ๐Ÿ’ฌ 520 ๐Ÿ“Œ 238

I am impeaching Secretary Kristi Noem, who is an incompetent leader and a disgrace to our democracy.

She wreaked havoc in the Chicagoland area and has brought her reign of terror to Minneapolis. One of her rogue ICE agents shot and killed an innocent woman today. It must come to an end.

08.01.2026 00:00 ๐Ÿ‘ 63680 ๐Ÿ” 14322 ๐Ÿ’ฌ 2231 ๐Ÿ“Œ 1291
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The actionable transcriptome: a framework for incorporating RNA sequencing into precision oncology Nature Reviews Clinical Oncology, Published online: 05 January 2026; doi:10.1038/s41571-025-01110-1RNA sequencing (RNA-seq) is increasingly being integrated into molecular tumour profiling but remains underutilized for clinical decision-making. This Perspective presents a framework for assessing the therapeutic, diagnostic and prognostic actionability of RNA-seq findings as well as an โ€˜actionable transcriptomeโ€™ list to help guide the application of RNA-seq findings in oncology practice.
05.01.2026 21:29 ๐Ÿ‘ 5 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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A CLOCK-targeting lncRNA induces trained immunity against tuberculosis Yu et al. discover that TRCR1, a tuberculosis resister-derived exosomal lncRNA, induces trained immunity via CLOCK-mediated epigenetic reprogramming. They show that mycobacterial protein MPT53 prompts...

lncRNA induces trained immunity against TB:

Exosomal lncRNA TRCR1 derived from Mtb resisters induces trained immunity via CLOCK-mediated epigenetic reprogramming. Mycobacterial MPT53 induces release of TRCR1+ exosomes. TRCR1 boosts immunity & BCG efficacy
www.cell.com/cell-host-mi...

02.01.2026 19:13 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Cooperative boron-copper catalysis unlocks alkyl radicals from amines Amines are popular nucleophiles in two-electron cross-coupling reactions, but their direct use as alkyl radical precursors is rare. Recently, Leonori and colleagues reported a direct strategy for triggering radical reactivity from amines via a thermodynamically favorable ฮฒ-scission that promotes a stable N=B ฯ€-bond. This report assesses the significance of these findings to aid in the activation of other valuable feedstock chemicals.

Online now: Cooperative boron-copper catalysis unlocks alkyl radicals from amines

20.12.2025 13:42 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Atmospheric-pressure ammonia synthesis on AuRu catalysts enabled by plasmon-controlled hydrogenation and nitrogen-species desorption - Nature Energy Conventional ammonia synthesis is energy intensive. Here the authors explore the mechanism of light-driven ammonia synthesis through in situ spectroscopy and modelling, and demonstrate that certain AuRu plasmonic alloys are promising catalysts for this potentially more sustainable process.

New research explores the mechanism of light-driven ammonia synthesis and demonstrates Au-Ru plasmonic alloys as promising catalysts.

17.12.2025 11:15 ๐Ÿ‘ 1 ๐Ÿ” 1 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 0
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Trump orders oil tankers blockade in Venezuela, labels Maduro regime a "terrorist" group The escalation exerts unprecedented pressure on the Maduro regime, threatening to bankrupt Venezuela's already struggling economy.

The blockade of Venezuela is a disgusting echo of U.S. imperialism in Latin America. We were lied to about Iraq and WMDs, and an entire generation paid the price.

Here we are again.

We cannot let a wannabe dictator drag us into another forever war.

www.axios.com/2025/12/17/t...

17.12.2025 00:56 ๐Ÿ‘ 15969 ๐Ÿ” 4644 ๐Ÿ’ฌ 776 ๐Ÿ“Œ 266

Iโ€™ll block everyone on LinkedIn who works in Palantir. Donโ€™t connect with me.

09.12.2025 07:04 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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MacKenzie Scott: *donates $50M every 10 hoursยฐ

Joe Lonsdale, co-founder of Palantir: "I want to see people hang"

07.12.2025 00:15 ๐Ÿ‘ 15776 ๐Ÿ” 3886 ๐Ÿ’ฌ 708 ๐Ÿ“Œ 242
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@seisydney.bsky.social @aseh.bsky.social @aussts.bsky.social @aehhub.bsky.social

25.11.2025 20:48 ๐Ÿ‘ 9 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Pleased to see (thanks to Heekyong Burge) my latest book There Is No Such Thing as Western Science: The Challenge from Postcolonial Science and Technology Studies, collected and translated by Jongsik Yi (Wonju: Eum, 2025) - available in good Korean bookstores. Not in English!
#STS #histstm #histsci

22.11.2025 02:46 ๐Ÿ‘ 17 ๐Ÿ” 5 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Get Primed on #Leishmaniasis with our NEW PrimeView! FREE to download this week! https://www.nature.c...

20.11.2025 21:16 ๐Ÿ‘ 6 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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How to fix genetic โ€˜nonsenseโ€™: versatile gene-editing tool could tackle a host of diseases Synthetic RNA molecules can program cells to ignore DNA mutations that interfere with protein production.

The method might one day overcome a key stumbling block faced by gene-editing therapies: the need to design a bespoke treatment for each disease

go.nature.com/4a0QoQ6

20.11.2025 09:35 ๐Ÿ‘ 12 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Yikes yikes yikes ๐Ÿ˜Ÿ

20.11.2025 02:56 ๐Ÿ‘ 31 ๐Ÿ” 8 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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RFK Jr.โ€™s Miasma Theory of Health Is Spreading The NIH is picking up Robert F. Kennedy Jr.โ€™s argument that a healthy immune system can keep even pandemic germs at bay.

โ€œMiasma theoryโ€ stages a comeback in the United States

Deep sigh ๐Ÿ˜ฎโ€๐Ÿ’จ

www.theatlantic.com/health/2025/...

19.11.2025 23:48 ๐Ÿ‘ 47 ๐Ÿ” 15 ๐Ÿ’ฌ 9 ๐Ÿ“Œ 5

Bro I got off from the waitlist to the Marine Geochemistry class

Celebrating ๐Ÿฅณ๐ŸŽ‰

15.11.2025 09:48 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Really wish I had gotten a better shot of this but holding a phone that says โ€œwho else was just โ€˜following ordersโ€™?โ€ up to a riot cop is hard as hell

11.11.2025 06:18 ๐Ÿ‘ 7027 ๐Ÿ” 1688 ๐Ÿ’ฌ 59 ๐Ÿ“Œ 51
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Global dust impacts on biogeochemical cycles and climate Nature Reviews Earth & Environment, Published online: 11 November 2025; doi:10.1038/s43017-025-00734-2Aeolian dust deposition can deliver nutrients that fuel primary production in remote ocean regions. This Review considers how dust sources and nutrient composition, in addition to dust flux, have potentially impacted ocean productivity, carbon burial and climate over the past 7โ€‰Myr.

New online! Global dust impacts on biogeochemical cycles and climate

12.11.2025 01:03 ๐Ÿ‘ 6 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Iโ€™m in the front row๐Ÿ—ฃ๏ธ๐Ÿ—ฃ๏ธ๐Ÿ—ฃ๏ธ

11.11.2025 06:37 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

The weathiest country in the world doesn't mean a thing if it wonโ€™t feed its own people.

09.11.2025 22:51 ๐Ÿ‘ 7400 ๐Ÿ” 1616 ๐Ÿ’ฌ 172 ๐Ÿ“Œ 44

He said that the agents would throw food at them to eat. The agents threatened to withhold food for a week and to beat him up if he didn't sign deportation papers. He said he saw others refuse and get beaten/receive no food. He signed because he was afraid.

07.11.2025 03:08 ๐Ÿ‘ 6049 ๐Ÿ” 1575 ๐Ÿ’ฌ 33 ๐Ÿ“Œ 148
book on shelf: โ€žmaking kin with treesโ€œ by solvejg nitzke. black and white image shows trees behind a large wall (are they tying to say hello? can we know what they are saying?)

book on shelf: โ€žmaking kin with treesโ€œ by solvejg nitzke. black and white image shows trees behind a large wall (are they tying to say hello? can we know what they are saying?)

look what i got in the mail! congrats to @nitzkesolvejg.bsky.social

07.11.2025 07:29 ๐Ÿ‘ 49 ๐Ÿ” 6 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
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DNA reference reagents isolate biases in microbiome profiling: a global multi-lab study | mSystems This benchmark paper highlights the true level of variability in microbiome data across the world and across sectors, underscoring the critical need for the use of WHO International DNA Gut Reference ...

๐ŸšจPaper alert! DNA reference reagents isolate biases in microbiome profiling: a global multi-lab study | mSystems journals.asm.org/doi/10.1128/...

27.10.2025 10:48 ๐Ÿ‘ 1 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Transition metal complexes as optical probes for super-resolution microscopy Nature Reviews Chemistry, Published online: 16 October 2025; doi:10.1038/s41570-025-00764-wSuper-resolution microscopy techniques can break conventional optical diffraction limits, but their performance can only be optimized by using probes with appropriate biophysical and photophysical properties. This Review highlights how transition metal complexes are being designed to meet these challenges.
18.10.2025 00:01 ๐Ÿ‘ 4 ๐Ÿ” 2 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

If itโ€™s not okay to be anti-fascism anymore, is it still okay to be pro-democracy? ๐Ÿค”

12.10.2025 21:21 ๐Ÿ‘ 6181 ๐Ÿ” 1072 ๐Ÿ’ฌ 242 ๐Ÿ“Œ 35
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Roberta Perkins: Sex Work, Feminism, and the Dawn of Transgender Activism in 1980s Australia In the 1980s, Australia witnessed the rise of its first transgender advocacy organisations. The most radical and pathbreaking of these was the Sydney-based Australian Transsexual Association (ATA)....

I am so happy to announce that my first peer-reviewed research paper is finally out! It is open access, so please have a read and let me know your thoughts!

Thank you so much to the lovely people at Australian Feminist Studies.

doi.org/10.1080/0816...

#AcademicSky #FeministSky #queeracademia

10.10.2025 00:29 ๐Ÿ‘ 25 ๐Ÿ” 8 ๐Ÿ’ฌ 6 ๐Ÿ“Œ 0