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Christine Moene

@cmoene

PhD student at the Netherlands Cancer Institute || gene regulation - epigenetics - genome organization || she/her

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19.09.2025
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Latest posts by Christine Moene @cmoene

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Functional maps of a genomic locus reveal confinement of an enhancer by its target gene Genes are often activated by enhancers located at large genomic distances, and the importance of this positioning is poorly understood. By relocating promoter-reporter constructs into thousands of alt...

✨Exciting news: the main story of my PhD is out in Science!

Together with Christine Moene @cmoene.bsky.social, we explored what happens when you scramble the genome—revealing how Sox2’s position shapes enhancer activation.

📖 Read the full story here: www.science.org/doi/10.1126/...

19.09.2025 14:09 👍 94 🔁 37 💬 3 📌 1

Have you ever wondered how the exact location of a gene affects it's activity?

The main story of my PhD deals with exactly that question, and is now published in Science! ✨
www.science.org/doi/10.1126/...

My amazing co-author and friend @mathiaseder.bsky.social summarized the highlights for you

19.09.2025 14:22 👍 36 🔁 13 💬 1 📌 2