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Simona Della Valle

@dellavallesimo

Synthetic biologist, farming microbes for sustainability • Research Associate @ UWA • Formerly PhD @ox.ac.uk @oxengsci.bsky.social • she/her

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16.01.2025
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Latest posts by Simona Della Valle @dellavallesimo

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Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system This study developed two simple, efficient, and rapid genome editing tools termed Self-splicing Intron-Based Riboswitch-Cas9 (SIBR-Cas9) and SIBR2.0-Cas12a, for editing the genome of the industrially relevant microbial strain Cupriavidus necator H16.…

Online now: Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system

16.03.2025 15:14 👍 0 🔁 2 💬 0 📌 0

🚨Check out this amwesome new CRISPR tool for highly efficient genome engineering in C. necator led by @dellavallesimo.bsky.social and @eorsi.bsky.social 🔥🔥🔥

14.03.2025 16:45 👍 2 🔁 1 💬 0 📌 0

Microbes like Cupriavidus necator naturally grow on #renewable feedstocks ♻️🧫 (CO₂, formate, hydrogen), yet their potential remains untapped due to the lack of efficient genetic tools... 1/2

www.cell.com/trends/biote...

16.03.2025 15:40 👍 7 🔁 4 💬 1 📌 0

Our new #CRISPR toolkit for C. necator, built on SIBR-Cas technology, is now in press - an incredible collaboration with @eorsi.bsky.social, @copabio.bsky.social and many others🧪🧬⏳✂

Check out the thread below for details on genome editing + controlling gene expression by splitting a gene in two!

17.03.2025 02:38 👍 3 🔁 0 💬 0 📌 0