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James Isbister

@james-isbister

Scientist @Open Brain Institute @openbraininst๐Ÿ‡จ๐Ÿ‡ญ Postdoc @EPFL_en Blue Brain Project DPhil @universityofoxford Precise neural coding principles (time-warped spike time patterns) Large biophysically-detailed brain models

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Latest posts by James Isbister @james-isbister

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#sfn2025 | James Isbister Travelling to #SfN2025 with a VR headset showing the incredible work of Marwan Abdellah and Michael Reimann who have developed algorithms to repair neuronal electron microscopy meshes and extract almo...

Check out our work to fully extract spines from EM at booth 3631 at #sfn2025 and learn how to analyse them on our brand new platform for brain simulation openbraininstitute.org/sfn-2025

13.11.2025 21:02 ๐Ÿ‘ 3 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1

Excited for whatโ€™s coming over the next 6 months

19.03.2025 10:40 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
The Open Brain Institute announces the dawn of a new frontier in neuroscience

The Open Brain Institute announces the dawn of a new frontier in neuroscience

Neuroscience is entering the digital age!

Today, we proudly launch the Open Brain Institute (OBI)โ€”a revolutionary non-profit organization dedicated to advancing neuroscience from the physical realm into the virtual world.

18.03.2025 13:27 ๐Ÿ‘ 3 ๐Ÿ” 3 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
Eye in the Sky by Hana Ajiashvili and Blue Brain Project
Eye in the Sky by Hana Ajiashvili and Blue Brain Project YouTube video by Hana Ajiashvili

To conclude the Blue Brain Project last year, composer Hana Ajiashvili presented music she wrote when she came across our visualizations online. It felt like she was making tangible hypotheses about the brain, and reminded me of how we think when we enter the field: www.youtube.com/watch?v=2h3I...

06.03.2025 09:57 ๐Ÿ‘ 3 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
An extended and improved CCFv3 annotation and Nissl atlas of the entire mouse brain
An extended and improved CCFv3 annotation and Nissl atlas of the entire mouse brain YouTube video by Blue Brain Project - EPFL

A beautiful video of the Blue Brain Project's improved CCFv3 annotation and Nissl atlas of the entire mouse brain building upon the @alleninstitute.bsky.social atlas. Recommend watching end-to-end. Great work by Sรฉbastien Piluso @cyrillefavreau.bsky.social and others

www.youtube.com/watch?v=upul...

09.12.2024 20:11 ๐Ÿ‘ 10 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Neurons warp space and time The messages sent between neurons look something like a Morse code, but the closer one looks the more mysterious the code becomes. The code is called the neural code and is the holy grail in neuroscie...

An old news article describing our finding of time-warped cortical spike time patterns. Looking forward to sharing our exciting new results on this soon

actu.epfl.ch/news/neurons...

09.12.2024 19:57 ๐Ÿ‘ 5 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
A morphologically-detailed model of rat somatosensory regions
A morphologically-detailed model of rat somatosensory regions YouTube video by Blue Brain Project - EPFL

Just a pretty video of our rat non-barrel somatosensory cortex model: actu.epfl.ch/news/empower...

www.youtube.com/watch?v=7g0q...

09.12.2024 19:48 ๐Ÿ‘ 3 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Spike sorting biases and information loss in a detailed cortical model https://www.biorxiv.org/content/10.1101/2024.12.04.626805v1

08.12.2024 01:15 ๐Ÿ‘ 17 ๐Ÿ” 4 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0