Shot. Chaser.
Shot. Chaser.
There's a consequence to the two parties being captured by extreme online opinions
@gallup.com polls show record high fraction of Americans consider themselves Independent with GenZ / Millennials identifying >50% as independent
More @ news.gallup.com/poll/700499/...
I finally gave in to the old man in me π΄π»
My IDEs are no longer in dark mode. I have seen the light (mode)
Recent studies have shown by directing CAR-T Cells at B-cells (which make the autoantibodies that cause much of autoimmune damage), you not only eliminate the autoantibodies, but potentially "reset" the immune system to a healthier state
Literally a potential cure! benjamintseng.com/2025/12/car-...
Hard to tell if this is deliberate fine tuning or a strange product of how Chinese models need to be tuned so as to NOT disagree with the stance of the CCPπ¨π³
But underscores some of the risks associated with using Chinese models
Shocking but not at the same time
Chinese DeepSeek model (the 670B reasoning one) produces 50% more security vulnerabilities when a politically sensitive "trigger word" (eg Taiwan, Tibet, Uyghur) is present in the request
www.crowdstrike.com/en-us/blog/c...
The final Buffett letter includes this charming anecdote & suggestion to us all on how to live a good life
Text of the full letter: www.berkshirehathaway.com/news/nov1025...
I'm generally optimistic about AI technology (yes, even for our careers) ... with one exception, and the data is starting to prove my fears right
benjamintseng.com/2025/11/whos...
#ChemSky
Turning 40 is a milestone that should come with a manual. All I got were these lessons instead -- hopefully they help (or at least amuse) you
Read all about the 7 lessons in full here: benjamintseng.com/2025/10/seve...
Lesson 7: Play stupid (status) games, win stupid prizes
Status games are everywhere (ask any parent of young kids the last time an ad or article made them feel guilty).
Recognize them and consciously decide which ones are actually worth your time and energy
Lesson 6: Good taste is overrated
In your career, good taste is an asset
In life? Itβs better to have low standards. Being easy to please (ie with wine, movies, food) is a superpower for everyday contentness. It saves you time, money, and mental energy for what truly matters.
Lesson 5: Genius doesn't generalize
In an age of influencer marketing & interview podcasts, its important to remember what it takes to be brilliant at one thing comes at the expense of others
TLDR: don't ask a gymbro for relationship advice or a VC about how to help the poor
2020 was a hard year. I was unemployed w a young son & aging parents I couldn't see
But it was also the year I built a telemedicine operation 0-to-1, built AI models which made it into academic papers, and did policy work which led to new friends & opptys
Embrace the unlikely
Lesson 4: Embrace the unlikely
My 30s included my getting fired, a pandemic, 9% inflation, US political re-alignment, my being put on a legal witness stand β all things I thought were unlikely.
Prepare for what you can, but also learn to embrace the unlikely...
Lesson 3: Thereβs little upside in talking about politics
Modern political discourse is about tribal outrage. It leads to bad policy and bad behavior.
Disengage from the daily outrage cycle and focus on *policy*. It's boring, but that's a feature, not a bug
Knowing someone is a doctor tells you a great deal about their education, income, and views on risk & credentials.
Knowing someone is a politician tells you they're professional fundraisers and popularity contest winners, and that they're structurally surrounded by flatterers
Lesson 2: A profession gives an oddly effective read on a person
Careers shape our incentives, skills, and definitions of success/failure. While not the whole story, knowing what someone does for a living offers a surprisingly useful set of heuristics for understanding them.
Lesson 1: Don't partner with someone until you've seen them in a crisis
Itβs easy to be open & giving when things are good. It's the bad times that reveal value & priorities. Before you enter a partnership (π° or β€), see how they handle a storm
My 30s were a wild decade of learning things about being a parent & about how the world works. As I head into the next decade, I've been reflecting on the lessons that have reshaped how I see the world.
Here are 7 of them. π§΅
How you know it's time to start thinking about selling...
Gene therapy for Huntington's Disease shows 75% slowdown in progression over 36 month clinical trial!
Amazing feat β working gene therapy + targeted surgery + synthetic control arm β and for company uniQure (who's seeing a 3x stock price bump on the news)
benjamintseng.com/2025/09/gene...
Why are ultra-processed foods bad for you? benjamintseng.com/2025/09/why-...
Death from sub-acute sclerosing panencephalitis (SSPE) in a child in Los Angeles
SSPE is a rare sequel of #measles infection that appears years after the initial infection, and is uniformly fatal. So sorry for this family. As things are going on the US, we'll be seeing more of these cases.
The Surrealism of Authoritarianism -- a look at life under Xi Jinping outlines some of the hallmarks of authoritarian rule benjamintseng.com/2025/09/the-...
You are buying this shirt because you're a Swiftie
I'm buying this shirt to protest the Chinese Communist party
We are not the same π€£
Listening to a medical informatics professor talk to a Med Student who thought he could vibe code through a data analysis & fail because he doesnt understand how the code or the data works π€¦π»ββοΈ
Vibe coding can be great: but don't use it where it matters if you can't check it
Amazing technical feat but does this not defeat the purpose of block chain as distributed ledger if you need to rely on a database hosted at a cloud provider?
How blockchain network Keeta processes 11 million transactions per second with Spanner | Google Cloud Blog share.google/dvfJQGpayOBh...
Are we at the start of a new golden age of antimicrobial discovery?
The lower cost of metagenomics + our better understanding of biosynthetic gene clusters + new computational methods = we may outrun the awful "end of antibiotics" that's fast approaching
benjamintseng.com/2025/08/new-...
This is a good thing in the neverending war on weaponized misinformation
If only we could get X to do the same... www.cnbc.com/2025/07/21/y...