Will Fuller

PhD Studentship in Molecular Physiology – Protein-Protein Interactions and Therapeutic Targeting of Cardiac Ion Channels at University of Glasgow on FindAPhD.com PhD Project - PhD Studentship in Molecular Physiology – Protein-Protein Interactions and Therapeutic Targeting of Cardiac Ion Channels at University of Glasgow, listed on FindAPhD.com

Delighted to invite applications for a PhD project in the group. Come and do some awesome biochemistry and physiology in a truly interdisciplinary team!

www.findaphd.com/phds/project...

Research Assistant/Associate at University of Glasgow Apply for the Research Assistant/Associate role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.

Well here’s an exciting opportunity! Who wants to spend 5 years working on S-acylation as part of a fantastic multidisciplinary team? #acylation #cellbiology #glasgow
www.jobs.ac.uk/job/DNB111/r...

My esteemed colleagues will buy you a drink!

This month is Heart Month! Professor Will Fuller explains what his research is about.

Will Fuller’s research group works on cellular and molecular mechanisms that control normal physiology in the heart, and how these things stop working properly to cause disease. (1/4)

Pass it on.
#StandWithUkraine

Thanks Dale! I’ll be working on the Addgene submission this weekend. We will share these reagents far and wide I hope.

Massive thanks to the amazing people in my lab who contributed to this study, to collaborators who generously shared reagents, and to @thebhf.bsky.social for funding.

And using a nanobody that binds the L-type calcium channel we depalmitoylate the pore forming subunit, shifting its voltage dependence and suppressing #arrhythmias in stem cell derived myocytes.

Using tricks developed by others to control the timing of nanobody binding, we built in a way to control when a protein is #palmitoylated or #depalmitoylated. We can induce target protein #depalmitoylation within an hour

Nanobody-thioesterase chimeras to specifically target protein palmitoylation - Nature Communications Reversible palmitoylation regulates the activity and localisation of numerous proteins. Here, Kuo et al develop nanobody-based reagents to specifically target palmitoylation of individual proteins, us...

Soooo excited to share this, just published. www.nature.com/articles/s41.... It started as a crazy ‘Friday afternoon’ experiment and just… worked. And kept on working. We fused a #nanobody to a #thioesterase. This delivers the thioesterase to a target and specifically depalmitoylates this protein

Why have you changed dozens of instances of ‘alpha1C’ in our manuscript to ‘alpha1 C’? It isn’t a unit. It was right the first time.

Daybreak on the morning run 😍

Frozen hair, frozen eyebrows, frozen everything on Beinn Udlamain and Sgàirneach Mhòr today! First hill of the year. Great to be out!

A day making music in a beautiful location. Saint Seans and Strauss and an appreciative audience!

Two papers accepted in one week caps a remarkable year of success. There have been difficult and fallow years in my career. This has not been one of them and I will celebrate that! Cheers! 🎉☃️🎄

BBSRC injects £20 million into long-term discovery research BBSRC is backing four major research projects to help pioneer critical advances in healthy ageing, drug discovery and sustainable agriculture.

www.ukri.org/news/bbsrc-i...
Well, this is very exciting. A welcome boost to S-acylation research in the UK. Very much looking forward to working as part of a fantastic team

A vote without a vote: the Saudi World Cup is an act of violence and disdain | Barney Ronay The shamelessness of Fifa’s process was fully on show in Zurich during a display of contempt for governance, democracy, love, hope and good sense

Give us your acclaim. Or don’t. It won’t really matter either way.
They used to pretend there was a vote. Now they don’t even bother with that #fifa #corrupt
www.theguardian.com/football/202...

Community sense check required… Reviewer asked us to show using proteomics that our new reagent doesn’t have off target effects. In a whole cell proteome, expression of one protein (our reagent) has changed. Reviewer: now you need to look at proliferation and viability assays. Feels unreasonable?

Exciting opportunity for a really cool PhD project! www.gla.ac.uk/postgraduate...

Lab Christmas party! 🎉 🥳

Tentsmuir beach, December sunshine 😍

We provide recordings of all lectures at the end of each block. Based on my colleagues experience this week 25 out of my class of 80+ will show up this morning. I massively value the opportunity to deliver teaching in person… but it is not particularly highly valued by the student body.

Empty lecture room

Empty lecture room

I love teaching in this space. Millions of times better than the lecture theatres I endured during undergrad days. Now I just have to hope the students turn up ready to hear about #lipidrafts

Stone arches with string lights lit up on the stone columns

Our first post on Bluesky - the beautiful Cloisters and their twinkling string winter lighting @uofglasgow.bsky.social

Follow us to read about the amazing research stories and projects being undertaken across our campuses.

👋 + 🙏

One week on here and am already connected to a much bigger network than I managed in the other place. And no bots! #betterplace

go.bsky.app/HqEcaCw

👋 + 🙏

👋🙏

May be a bit premature, but here is the Starter Pack I am trying to populate for #IonChannel research. Ping me and I’ll add you obviously! (Or to be removed)
go.bsky.app/6taxHfx
@jgenphysiol.bsky.social @auditorynerves.bsky.social @plesslab.bsky.social @rainbowlabuol.bsky.social