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Nils Homer

@nilshomer.com

I write software for Biologists. Founder @fulcrumgenomics, Bioinformatician, Computer Scientist, Coder, Father of 2xGirls. Opinions are my own.

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31.08.2023
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Latest posts by Nils Homer @nilshomer.com

"AGBT meet your new bioinformatics team" with hand-drawn portraits of Nils Homer and Tim Fennell

"AGBT meet your new bioinformatics team" with hand-drawn portraits of Nils Homer and Tim Fennell

@tfenne.bsky.social and @nilshomer.com are on the ground at #AGBT2026 this week.

Big data. Tight timelines. Real decisions.

#Bioinformatics is where complexity becomes something teams can actually use.

If you’re here, let’s connect.

23.02.2026 14:52 👍 3 🔁 4 💬 0 📌 0

So long Scala, thanks for all the fish.

24.01.2026 08:39 👍 1 🔁 0 💬 0 📌 0

You have my email... I could be... convinced...

22.01.2026 01:50 👍 3 🔁 0 💬 0 📌 0
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Core Value: Valuing People Fulcrum Genomics 10th Anniversary Series

10th Anniversary Core Values blog series: Valuing People

Valuing People is one of our deepest commitments: to ourselves, to our team, and to our clients. Life is messy—just like biology. When life gets complicated, we don’t look away. We step in.

Read More: blog.fulcrumgenomics.com/p/core-value...

23.10.2025 19:35 👍 4 🔁 4 💬 0 📌 0
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@plasmidsaurus.bsky.social next time in Boston for #ASHG25, consider catering with Bagelsaurus!

20.10.2025 22:40 👍 4 🔁 0 💬 0 📌 0

Ever want a live code review of your #bioinformatics code?

DM me if you’re at #ASHG25 and I’ll take look to give you suggestions on how to improve reproducibility, maintainability, and overall engineering quality.

14.10.2025 22:10 👍 10 🔁 2 💬 0 📌 0
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Core Value: Openness Fulcrum Genomics 10th Anniversary Series

10th Anniversary Core Values blog series: Openness

Openness is an action. It’s a positive, and proactive, choice to lean-in.

It begins with a simple but powerful question: What do I know that others need to know?

Read more: blog.fulcrumgenomics.com/p/core-value...

02.10.2025 17:52 👍 2 🔁 2 💬 0 📌 0

I'll be there to prove I'm not an AI. Lets meet up!

30.09.2025 17:59 👍 1 🔁 0 💬 0 📌 0

@nilshomer.com, Yossi Farjoun, and @tfenne.bsky.social will be attending #ASHG25 in Boston this year on behalf of Fulcrum Genomics. Let us know if you'll be there too!

25.09.2025 09:39 👍 2 🔁 2 💬 0 📌 1

@nilshomer.com, Yossi Farjoun and I will be attending ASHG in Boston this year on behalf of Fulcrum Genomics. Let us know if you'll be there too!

18.09.2025 15:19 👍 4 🔁 1 💬 0 📌 0

The Charles river doesn’t have trees… just saying.

10.08.2025 02:39 👍 0 🔁 0 💬 1 📌 0
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Ten Years of Fulcrum Genomics Fulcrum Genomics Founded July 27, 2015

Here’s to another ten years working with awesome and talented people on challenging and impactful Bioinformatics problems!

blog.fulcrumgenomics.com/p/ten-years-...

28.07.2025 14:28 👍 10 🔁 1 💬 0 📌 0
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Meet Erin McAuley Scaling Science Without Losing the Plot

We love working with people who notice how things fit together, who make unwieldy problems work better. The 'Meet the Team' series spotlights humans behind our bioinformatics work. We hope you'll feel like you've met us — or want to. Meet Erin McAuley: blog.fulcrumgenomics.com/p/meet-erin-...

23.07.2025 14:44 👍 6 🔁 4 💬 0 📌 0

Remember, to be generous also means accepting help to allow others the opportunity to be generous. You cannot give that which you do not have.

23.07.2025 08:12 👍 4 🔁 0 💬 0 📌 0

Rather than feeling unworthy or like a burden, I choose to be grateful for the time they shared, giving them the chance to be generous and reaffirming my own value.

23.07.2025 08:12 👍 0 🔁 0 💬 1 📌 0

I regularly volunteer my time meet with folks in the field. Instead, today reached out for guidance and help, and I was met with generosity as someone took the time to meet with me.

23.07.2025 08:12 👍 0 🔁 0 💬 1 📌 0

Saying no when someone offers to help deprives them of the opportunity to be generous.

23.07.2025 08:12 👍 2 🔁 1 💬 1 📌 0
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Fix This Sign

What's the equivalent in #bioinformatics?

xkcd.com/3113/

12.07.2025 01:16 👍 4 🔁 1 💬 3 📌 1
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My Genetic Data are public Genomics, privacy, and the acquisition of 23andMe.

My Genetic Data are public: blog.fulcrumgenomics.com/p/my-genetic...

02.07.2025 21:25 👍 6 🔁 0 💬 0 📌 0

It's a "I don't want to have to write the same thing multiple times across clients" and "here's a look at the quality of code we write" and "community benefit is one of our core values"...

04.06.2025 16:56 👍 6 🔁 0 💬 0 📌 0
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Create conda recipes with Grayskull Master the Conda Universe

By the power of Grayskull...

blog.fulcrumgenomics.com/p/create-con...

27.05.2025 16:04 👍 3 🔁 0 💬 0 📌 1

Cunningham’s Law, but making feature requests to get the correct answer. There’s got to be a German word for that.

22.05.2025 04:48 👍 0 🔁 0 💬 0 📌 0
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Half the battle is knowing the right reference to use...

15.05.2025 16:31 👍 0 🔁 0 💬 0 📌 0

Join us and find out!

13.05.2025 16:15 👍 3 🔁 0 💬 1 📌 0
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Recent Open Source Work by Fulcrum Genomics Highlights from the last 3-4 months of our work in open source software

We try to be good #bioinformatics community members; check out our recent Open Source work @fulcrumgenomics.com
blog.fulcrumgenomics.com/p/recent-ope...

13.05.2025 16:04 👍 10 🔁 2 💬 1 📌 1
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.gitconfig GitHub Gist: instantly share code, notes, and snippets.

git mav

gist.github.com/nh13/0f32244...

05.05.2025 18:38 👍 2 🔁 0 💬 0 📌 0
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a man is covering his mouth with his hand and says `` and like that ... he 's gone . '' ALT: a man is covering his mouth with his hand and says `` and like that ... he 's gone . ''

"As of May 1st 2025, GATK forums will be community-driven and self-moderated. They will not be moderated or monitored by a GATK team member."

See more: gatk.broadinstitute.org/hc/en-us

30.04.2025 16:34 👍 2 🔁 0 💬 0 📌 0
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Single duplex DNA sequencing with CODEC detects mutations with high sensitivity - Nature Genetics Concatenating Original Duplex for Error Correction (CODEC) is a method that concatenates both strands of each DNA duplex to enable highly sensitive mutation detection in a range of analytes with fewer...

fgbio in use again!

Who says we can't have OSS #bioinformatics from an commercial organization?

www.nature.com/articles/s41...

28.04.2025 17:12 👍 7 🔁 1 💬 0 📌 0
A Python programming snippet that uses pytest, pytest fixtures, advanced use of fixtures, monkey patching the OS environment, type hinting, mocking impure environments, and generators.

A Python programming snippet that uses pytest, pytest fixtures, advanced use of fixtures, monkey patching the OS environment, type hinting, mocking impure environments, and generators.

Python is a simple language, but using it isn't always easy.

Today I reflected on the following code. To really understand it, one must learn: generators, type hinting, pytest fixtures, advanced usage of fixtures, monkey patching the OS environment, mocking impure environments, generators...

16.04.2025 01:52 👍 4 🔁 1 💬 0 📌 0
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www.harvard.edu/about/divers...

15.04.2025 01:30 👍 2 🔁 0 💬 0 📌 0