The Protein Data Bank (#PDB) has reached a new milestone: 250,441 entries in the archive, a record since its founding in 1971, all thanks to the efforts and contributions of the structural biology community.
⬇️ more ⬇️
www.wwpdb.org/news/news?ye...
#StructuralBiology
Congrats!!
Looking for motivated postdocs interested in doing exciting research at the intersection of immunology and regenerative biology. We use intravital two-photon imaging to track and manipulate immune cell behavior at the single-cell level in live animals mesa-lab.org Apply: apply.interfolio.com/180660
🎊🎉🥳
🧬🔬@science.org A genetically encoded device for #transcriptome storage in mammalian cells | Science www.science.org/doi/10.1126/... @broadinstitute.org
Someone was asking about doughnuts the other day.
😍 Whats your rig?
🥳🥳🎉🥳
cryo-em doughnut
In the neighborhood of 2Å. Sometimes I find a few in the better parts of a 2.3Å map.
Calling all structural biologists in the NYC metro area! The nysbdg.bsky.social is back for yet another gathering for 2025!
Register here 👉🏼 buff.ly/N42ul1b
I look forward to seeing you there! 😎
#structuralbiology #cyrstallography #cryoEM #NMR
#chromatography #proteinpurification #AKTAsystems
Our lab is seeking a Postdoctoral Fellow. The position is intentionally broad, as we are looking for outstanding researchers from diverse scientific backgrounds to advance our understanding of cilia and ciliopathies: academicpositions.harvard.edu/postings/15526
My first impression is that the heterogeneity isn't going to be the biggest challenge. I'm already pulling my hair over symmetry and anisotropy. 🙃
#CAHRA2025 #CompHet #CryoEM
Pretty excited about this "2025 Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms" #CAHRA2025
https://heterogeneity.notion.site/challenge
I started looking at the compositional heterogeneity challenge (#CompHet), some very weird things in there. Curious to figure out […]
Announcing cryo-EM heterogeneity challenge #2, now dubbed the 2025 Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms (CAHRA)! Join us for a webinar next Friday (Nov 14th) to learn more. Datasets already posted here: heterogeneity.notion.site/challenge #cryoem
#CryoEM how do we feel about this instrument? We may be in the market and I want to know what people are currently using.
I did. It lived in my 1M NaOH stock.
Hummm
This is an auto include on my reading list because I know its going to be good. Congrats @vcushing.bsky.social @bjgreber.bsky.social and all!
When Macrophages Disappear, Skin Blood Vessels Age!
Check out our new study @nature.com that uncovers how the loss of capillary-associated macrophages with age blocks vessel repair and blood flow, revealing a new cellular trigger of tissue aging. #Aging #Immunology
👇👇
www.nature.com/articles/s41...
We have an open post-doc position in my group to study mRNA cleavage and polyadenylation using biochemical reconstitution and cryoEM.
Please get in touch if you are interested in joining this amazing team! 🔬🧬🤩
#RNA #cryoEM
Juan B. Rodriguez Molina
Congrats to #LMBAlumni Juan B. Rodriguez Molina, former Investigator Scientist in the LMB's Structural Studies Division, newly appointed Assistant Professor in the Dept of Molecular and Cellular Biosciences at the University of Cincinnati College of Medicine
researchdirectory.uc.edu/p/1818215
Looks good! Looking forward to the preprint because i’m keen on how you did this.
Important to remember the theoretical size limit is based on assumptions and a model that may or may not be complete. It isn't some indisputable universal truth.
Hey thats me.
Since when are vaults cool again? Loving it
My lab has developed mSHINE, allowing for both highly multiplexed and portable nucleic acid detection. Very exciting work led by the talented @sijbren-kramer.bsky.social, who is off to do a PhD at Stanford at the end of the month!
Now out in Science Advances: www.science.org/doi/10.1126/...
😍😍😍
Excited to share our latest work with @simonbullock11.bsky.social! We looked at how diverse mRNAs get selected for subcellular localization and it turns out that a single protein can recognize different RNA elements using shared features that weren’t apparent before.
www.biorxiv.org/content/10.1...
