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Jon Grimm

@dyerfulchymist

Senior scientist and synthetic organic chemist working on fluorophore development in the Lavis lab at HHMI Janelia

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07.02.2024
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Latest posts by Jon Grimm @dyerfulchymist

Oh good, so I guess the AI bubble pop / economic collapse is going to coincide with a global oil crisis AND a war? Cool cool cool.

06.03.2026 23:54 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Unexpected?

06.03.2026 18:09 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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This is not good.

06.03.2026 13:40 πŸ‘ 9684 πŸ” 3708 πŸ’¬ 761 πŸ“Œ 468

Hmm, I'd swear we've seen this type of floor plan before, but I just... can't... put... my finger... on it...

20.02.2026 15:27 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

But bears like Coke πŸ€·β€β™‚οΈ

09.02.2026 00:34 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Preview
Should You Buy a Newspaper or a Yacht? Advice for Jeff Bezos

www.theatlantic.com/newsletters/...

06.02.2026 03:29 πŸ‘ 168 πŸ” 33 πŸ’¬ 9 πŸ“Œ 5

Jeff Bezos’s wealth has increased an average of $70 million every day of 2026, meaning that he could have offset The Post’s losses with what he’s made since Monday.

05.02.2026 02:48 πŸ‘ 15314 πŸ” 4643 πŸ’¬ 445 πŸ“Œ 250
Preview
New reagents take the burn out of butyllithium Merck KGaA's non-pyrophoric butyllithium in poly(Ξ±-olefin) oil make BuLi stable to air and water

As someone who has used nBuLi a lot, 10 molar and rarely even tBuLi too, this sounds very interesting.
I’ll never forget holding a syringe with 50 ml 10 M BuLi when an earthquake magnitude 6.6 struck… I was fine!
#chemchat #chemsky
www.chemistryworld.com/news/new-rea...

21.01.2026 14:26 πŸ‘ 18 πŸ” 4 πŸ’¬ 3 πŸ“Œ 0
This line graph illustrates the percentage change in agency staff levels from the previous year for nine major U.S. federal scientific and health organizations between the fiscal years 2016 and 2025. The agencies tracked include the CDC, Department of Energy, EPA, FDA, NASA, NIH, NIST, NOAA, and NSF. For the majority of the timeline between 2016 and 2023, the agencies show relatively stable fluctuations, generally staying within a range of +5% to -5% change per year. However, there is a dramatic and uniform plummet starting in the 2024–25 period. Every agency depicted shows a sharp downward trajectory, with staffing losses ranging from approximately -15% to over -25%. The Environmental Protection Agency (EPA) shows the most significant decline, dropping to roughly -26%, while the National Institute of Standards and Technology (NIST) shows the least severe but still substantial drop at approximately -15%.

This line graph illustrates the percentage change in agency staff levels from the previous year for nine major U.S. federal scientific and health organizations between the fiscal years 2016 and 2025. The agencies tracked include the CDC, Department of Energy, EPA, FDA, NASA, NIH, NIST, NOAA, and NSF. For the majority of the timeline between 2016 and 2023, the agencies show relatively stable fluctuations, generally staying within a range of +5% to -5% change per year. However, there is a dramatic and uniform plummet starting in the 2024–25 period. Every agency depicted shows a sharp downward trajectory, with staffing losses ranging from approximately -15% to over -25%. The Environmental Protection Agency (EPA) shows the most significant decline, dropping to roughly -26%, while the National Institute of Standards and Technology (NIST) shows the least severe but still substantial drop at approximately -15%.

This is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again.

www.nature.com/immersive/d4...

20.01.2026 22:53 πŸ‘ 14446 πŸ” 8315 πŸ’¬ 90 πŸ“Œ 765
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21-year-old activist injured by ICE:

I will be blind for life. I have fractures in my skull that they can't fix. They pulled a piece of plastic the size of a nickel out of my eye. I had shards of metal, glass, and plastic behind my eye and in my skull. They said it was a miracle I survived.

15.01.2026 19:24 πŸ‘ 5903 πŸ” 2558 πŸ’¬ 223 πŸ“Œ 278
A family member reacts after a federal immigration officer used a battering ram to break down a door before making an arrest on January 11, 2026, in Minneapolis.

A family member reacts after a federal immigration officer used a battering ram to break down a door before making an arrest on January 11, 2026, in Minneapolis.

Stunning photos from Minneapolis, including this one by John Locher for the Associated Press. www.theatlantic.com/photography/...

15.01.2026 19:22 πŸ‘ 18014 πŸ” 7513 πŸ’¬ 916 πŸ“Œ 821

As one of your constiuents, thank you @repsuhas.bsky.social for having the spine that so many of your colleagues completely lack.

15.01.2026 15:42 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Give them to me cause I'm good at keeping secrets

15.01.2026 03:43 πŸ‘ 155 πŸ” 27 πŸ’¬ 9 πŸ“Œ 2
Preview
Stand With Minnesota: Resource Hub Causes to Donate to in Minnesota to Help Our Communities Defend Themselves from ICE This list is now available/shareable at standwithminnesota.org *Note: I am from Minnesota, and these come from peo...

For people elsewhere who have asked how to support Minnesota while we’re overrun with nazi thugs, here’s an excellent list of places that could use financial help. Lots of choices. Thank you so much!

docs.google.com/document/d/1...

15.01.2026 02:48 πŸ‘ 3395 πŸ” 2680 πŸ’¬ 17 πŸ“Œ 55

Non-protesting dad just trying to hustle his kids, as young as 6mo, out of the neighborhood. ICE threw a flash-bang INTO HIS car, all 6 kids in the hospital now.

If anyone wondered how things turn against occupying armies there's a case study playing out in front of you.

15.01.2026 04:27 πŸ‘ 17831 πŸ” 8369 πŸ’¬ 302 πŸ“Œ 490
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This dude is intense and correct

15.01.2026 09:05 πŸ‘ 9220 πŸ” 2961 πŸ’¬ 96 πŸ“Œ 370

My daughter's school in Richfield, MN (adjacent to Minneapolis) is closing tomorrow due of out-of-control federal agents. Fourth graders spent the week building walls of snow at recess to protect their classmates from ICE. This isn't about immigration enforcement, it's about terror.

15.01.2026 12:54 πŸ‘ 4619 πŸ” 1506 πŸ’¬ 69 πŸ“Œ 108

That is what was relayed

15.01.2026 04:09 πŸ‘ 3739 πŸ” 1593 πŸ’¬ 100 πŸ“Œ 252

In America you drop your kid off at school, get your brains blown out on the ride home, then the Vice President drops everything for a week to call you a terrorist, to slander your family, to protect the circumstances that led to your death so they can do it again. It is government by Alex Jones.

09.01.2026 19:24 πŸ‘ 45443 πŸ” 11655 πŸ’¬ 756 πŸ“Œ 274
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Make it viral.

08.01.2026 03:22 πŸ‘ 47647 πŸ” 21394 πŸ’¬ 360 πŸ“Œ 528

what you clearly see, CLEARLY, is a driver who is spooked by the agents grabbing her door, takes steps to drive away, and is immediately shot as moves her vehicle *away* from the agents.

08.01.2026 13:12 πŸ‘ 6231 πŸ” 1572 πŸ’¬ 127 πŸ“Œ 45

Forensic analysis of objective video evidence. This is how you serve readers searching for clarity.

08.01.2026 13:00 πŸ‘ 8820 πŸ” 4225 πŸ’¬ 308 πŸ“Œ 727

It’s genuinely wild that the United States spent decades building an elaborate rules-based international order which de facto cemented its permanent status as the dominant global hegemon, sustained by ideology rather than might, and now is just blowing it all up for literally no reason

06.01.2026 00:35 πŸ‘ 11235 πŸ” 2530 πŸ’¬ 429 πŸ“Œ 313
News Team,
These men risked their lives to speak with us. We have a moral
Thank you for the notes and texts. I apologize for not reaching out earlier.
and professional obligation to the sources who entrusted us
with their stories. Abandoning them now is a betrayal of the
Ilearned on Saturday that Bari Weiss spiked our story, INSIDE
most basic tenet of journalism: giving voice to the voiceless.
CECOT, which was supposed to air tonight. We (Ori and I) asked for a call to discuss her decision. She did not afford us
CBS spiked the Jeffrey Wigand interview due to legal
that courtesy/opportunity.
concerns, nearly destroying the credibility of this broadcast. It
Our story was screened five times and cleared by both CBS
took years to recover from that "low point." By pulling this story
attorneys and Standards and Practices. It is factually correct.
to shield an administration, we are repeating that history, but
In my view, pulling it now-after every rigorous internal check has been met is not an editorial decision, it is a political one.
for political optics rather than legal ones.
We requested responses to questions and/or interviews with
We have been promoting this story on social media for days.
DHS, the White House, and the State Department. Government
Our viewers are expecting it. When it fails to air without a
silence is a statement, not a VETO. Their refusal to be interviewed is a tactical maneuver designed to kill the story.
credible explanation, the public will correctly identify this as
If the administration's refusal to participate becomes a valid reason to spike a story, we have effectively handed them a "kill switch" for any reporting they find inconvenient.
corporate censorship. We are trading 50 years of "Gold
Standard" reputation for a single week of political quiet.
If the standard for airing a story becomes "the government must agree to be interviewed," then the government effectively
I care too much about this broadcast to watch it be dismantled
without a…

News Team, These men risked their lives to speak with us. We have a moral Thank you for the notes and texts. I apologize for not reaching out earlier. and professional obligation to the sources who entrusted us with their stories. Abandoning them now is a betrayal of the Ilearned on Saturday that Bari Weiss spiked our story, INSIDE most basic tenet of journalism: giving voice to the voiceless. CECOT, which was supposed to air tonight. We (Ori and I) asked for a call to discuss her decision. She did not afford us CBS spiked the Jeffrey Wigand interview due to legal that courtesy/opportunity. concerns, nearly destroying the credibility of this broadcast. It Our story was screened five times and cleared by both CBS took years to recover from that "low point." By pulling this story attorneys and Standards and Practices. It is factually correct. to shield an administration, we are repeating that history, but In my view, pulling it now-after every rigorous internal check has been met is not an editorial decision, it is a political one. for political optics rather than legal ones. We requested responses to questions and/or interviews with We have been promoting this story on social media for days. DHS, the White House, and the State Department. Government Our viewers are expecting it. When it fails to air without a silence is a statement, not a VETO. Their refusal to be interviewed is a tactical maneuver designed to kill the story. credible explanation, the public will correctly identify this as If the administration's refusal to participate becomes a valid reason to spike a story, we have effectively handed them a "kill switch" for any reporting they find inconvenient. corporate censorship. We are trading 50 years of "Gold Standard" reputation for a single week of political quiet. If the standard for airing a story becomes "the government must agree to be interviewed," then the government effectively I care too much about this broadcast to watch it be dismantled without a…

1. BREAKING

Sharyn Alfonsi, a correspondent for 60 Minutes, sent an internal email to colleagues stating that CBS News editor in chief Bari Weiss β€œspiked our story” about the Trump administration and the transfer of deportees to a prison in El Salvador.

22.12.2025 03:34 πŸ‘ 1367 πŸ” 469 πŸ’¬ 28 πŸ“Œ 41
News Team,
Thank you for the notes and texts. I apologize for not reaching out earlier.
I learned on Saturday that Bari Weiss spiked our story, INSIDE CECOT, which was supposed to air tonight. We (Ori and I) asked for a call to discuss her decision. She did not afford us that courtesy/opportunity.
Our story was screened five times and cleared by both CBS attorneys and Standards and Practices. It is factually correct. In my view, pulling it now-after every rigorous internal check has been met is not an editorial decision, it is a political one.
We requested responses to questions and/or interviews with DHS, the White House, and the State Department. Government silence is a statement, not a VETO. Their refusal to be interviewed is a tactical maneuver designed
to kill the story.
If the administration's refusal to participate becomes a valid reason to spike a story, we

News Team, Thank you for the notes and texts. I apologize for not reaching out earlier. I learned on Saturday that Bari Weiss spiked our story, INSIDE CECOT, which was supposed to air tonight. We (Ori and I) asked for a call to discuss her decision. She did not afford us that courtesy/opportunity. Our story was screened five times and cleared by both CBS attorneys and Standards and Practices. It is factually correct. In my view, pulling it now-after every rigorous internal check has been met is not an editorial decision, it is a political one. We requested responses to questions and/or interviews with DHS, the White House, and the State Department. Government silence is a statement, not a VETO. Their refusal to be interviewed is a tactical maneuver designed to kill the story. If the administration's refusal to participate becomes a valid reason to spike a story, we

have effectively handed them a "kill switch" for any reporting they find inconvenient.
If the standard for airing a story becomes
"the government must agree to be
interviewed," then the government effectively gains control over the 60 Minutes broadcast.
We go from an investigative powerhouse to a stenographer for the state.
These men risked their lives to speak with us.
We have a moral and professional obligation to the sources who entrusted us with their
stories. Abandoning them now is a betrayal of the most basic tenet of journalism: giving voice to the voiceless.
CBS spiked the Jeffrey Wigand interview due to legal concerns, nearly destroying the credibility of this broadcast. It took years to recover from that "low point." By pulling this story to shield an administration, we are repeating that history, but for political optics rather than legal ones.

have effectively handed them a "kill switch" for any reporting they find inconvenient. If the standard for airing a story becomes "the government must agree to be interviewed," then the government effectively gains control over the 60 Minutes broadcast. We go from an investigative powerhouse to a stenographer for the state. These men risked their lives to speak with us. We have a moral and professional obligation to the sources who entrusted us with their stories. Abandoning them now is a betrayal of the most basic tenet of journalism: giving voice to the voiceless. CBS spiked the Jeffrey Wigand interview due to legal concerns, nearly destroying the credibility of this broadcast. It took years to recover from that "low point." By pulling this story to shield an administration, we are repeating that history, but for political optics rather than legal ones.

We have been promoting this story on social media for days. Our viewers are expecting it.
When it fails to air without a credible
explanation, the public will correctly identify this as corporate censorship. We are trading 50 years of "Gold Standard" reputation for a single week of political quiet.
I care too much about this broadcast to watch
it be dismantled without a fight.
Sharyn

We have been promoting this story on social media for days. Our viewers are expecting it. When it fails to air without a credible explanation, the public will correctly identify this as corporate censorship. We are trading 50 years of "Gold Standard" reputation for a single week of political quiet. I care too much about this broadcast to watch it be dismantled without a fight. Sharyn

Per NY Times’s Michael Grynbaum on X, this is Sharyn Alfonsi’s email to her β€œ60 Minutes” colleagues in full:

22.12.2025 03:37 πŸ‘ 27408 πŸ” 10851 πŸ’¬ 679 πŸ“Œ 958

Via @liamjscott.bsky.social at the other site here’s the full email from 60 Minutes correspondent Sharyn Alfonsi. She’s putting her career on the line by fighting here. And she’s fighting for all of us.

22.12.2025 03:28 πŸ‘ 1280 πŸ” 486 πŸ’¬ 18 πŸ“Œ 37
Preview
'Everyone Disliked That' β€” Amazon Pulls AI-Powered Fallout Recap After Getting Key Story Details Wrong - IGN Amazon has pulled its AI-powered Fallout Season 1 recap after fans noticed it made significant errors ahead of the launch of Season 2.

Lolz, the hallucination engine can't even summarize a season of a TV show correctly. Hundreds of billions well-spent! www.ign.com/articles/eve...

16.12.2025 18:11 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

🀣🀣🀣
One drop of bΜΆlΜΆoΜΆoΜΆdΜΆ EiGhTy MoLeCuLeS!

04.12.2025 18:55 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

LLMs and generative AI are the enshittification of the human race.

25.11.2025 13:38 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Your speech was straight πŸ”₯, Kat, and you do such a good job distilling and articulating the anger and frustration so many of us are feeling right now. America will be a better place with you in Congress 🀞

24.11.2025 20:35 πŸ‘ 37 πŸ” 2 πŸ’¬ 2 πŸ“Œ 0