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Ben Engel

@cellarchlab.com

cellarchlab.com Univ. of Basel BiozentrumπŸ‡¨πŸ‡­. Exploring molecular architecture inside cells with #CryoEM #TeamTomo. Plants and algae in a changing climate. β„πŸ”¬ OF 🌿 4THE 🌍!

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Latest posts by Ben Engel @cellarchlab.com

So it turns out that chromatin in archaea takes the hellish form of a Lovecraftian tube worm πŸͺ±πŸ”₯

Love it! Thanks for the nightmare-fuel! 😱

#ArchaeaSky @dodonova-sveta.bsky.social πŸ§ͺ

28.02.2026 05:16 πŸ‘ 48 πŸ” 9 πŸ’¬ 3 πŸ“Œ 0
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@embl.org at its best: collaborative, open, transformative, and just the right amount of crazy. Dreaming of mechanistic cell biology *in the natural environment*? Dream no more, rent the AML.

www.biorxiv.org/content/10.6...

www.youtube.com/watch?v=jepb...

#WeFreezeOnTheBeach #ProtistsOnSky 🦠🌍πŸ§ͺ

24.02.2026 12:34 πŸ‘ 86 πŸ” 29 πŸ’¬ 3 πŸ“Œ 2

So one day, I walk into our lab and @computingcaitie.bsky.social & @abimoye.bsky.social are carying eyeballs around everywhere πŸ‘€. Thanks for the eye-opening collaboration! (literally, ha!) πŸ§ͺ

24.02.2026 22:22 πŸ‘ 18 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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Great to see our paper on light-intensity dependent swimming patterns in #Chlamydomonas out now in Phys Rev Lett. as an Editors' suggestion! With a nice commentary by @philipcball.bsky.social.

Chlamy actively modulate the beat planes of their #cilia!
journals.aps.org/prl/abstract... #protistsonsky

20.02.2026 16:54 πŸ‘ 73 πŸ” 24 πŸ’¬ 1 πŸ“Œ 1

Haha, I am notorious for my strong feelings on segmentation colors 🌈🎨 πŸ§ͺ

But did we pick the exact right shade of pink? Maybe we should try five more? πŸ’•

Pretty figure incoming @lowlab.bsky.social πŸ€—

20.02.2026 11:30 πŸ‘ 6 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

Histones in archaea, you say? Check out this new paper from @dodonova-sveta.bsky.social @embl.org 😁 πŸ§ͺ

bsky.app/profile/dodo...

17.02.2026 21:54 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Microtubules in Asgard archaea Microtubules are a hallmark of eukaryotes. Archaeal and bacterial homologs of tubulins typically form homopolymers and non-tubular superstructures. Th…

It's very cool! I already teach this awesome study from @florianwollweber.bsky.social & @pilhoferlab.bsky.social in my first-year cell bio class at the @biozentrum.unibas.ch

#ArchaeaSky #TeamTomo πŸ§ͺ

www.sciencedirect.com/science/arti...

17.02.2026 21:51 πŸ‘ 6 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Very cool environmental #CryoET. This is an exciting frontier for #TeamTomo πŸ§ͺ 🌍

13.02.2026 12:27 πŸ‘ 11 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I agree. Grandstanding without putting more money in the pot πŸ’°. Funding is tighter than ever this year, even in SwitzerlandπŸ‡¨πŸ‡­ …the @snsf.ch is taking a big hit 😣

12.02.2026 21:35 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thanks Khaled 🌱😊

11.02.2026 20:16 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Chloroplast-encoded small subunit extensions reshape the Chlamydomonas chlororibosome www.biorxiv.org/content/10.64898/2026.02.07.704542v1 #cryoEM

10.02.2026 09:10 πŸ‘ 8 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

This is absolutely gorgeous work from @helenfoster.bsky.social, @margotriggi.bsky.social, @gaiapigino.bsky.social and colleagues 🀩

#Chlamy cilia never cease to amaze!

10.02.2026 14:44 πŸ‘ 10 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

At long last, the Chlamy chloroplast ribosome hat 🎩 (now renamed the arm πŸ’ͺ) is here to say helloπŸ‘‹! We first spotted this extended structure in green algae a decade ago, and @florentwaltz.bsky.social did beautiful work bringing it into focus! #CryoEM ❄️ #TeamTomo πŸ”¬ #PlantScience 🌾 #ProtistsOnSky πŸ§ͺ

10.02.2026 13:53 πŸ‘ 50 πŸ” 11 πŸ’¬ 0 πŸ“Œ 0
Hot Topic Conference Support for an "Eduard Strasburger Hot Topic Conference" for DBG's members

For #ECR’s:

DBG’s Hot Tpoic Workshop
on Cryo-Electron Tomography + FIB-milling

13 – 15 April 2026
In @cellarchlab.com 's lab @biozentrum.unibas.ch

Organised by @tamb-o.bsky.social, Karen Zinzius, @fannyleblanc.bsky.social

Details: www.deutsche-botanische-gesellschaft.de/en/about-us/...

03.02.2026 17:24 πŸ‘ 11 πŸ” 8 πŸ’¬ 0 πŸ“Œ 1

Thanks Johann! Big congrats on your beautiful work as well. Really jaw-dropping #CryoET!! 🀩 I agree there are some cool parallels between the systems πŸ€“ πŸ§ͺ

31.01.2026 20:08 πŸ‘ 4 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Big thanks to @nanoscience.ch πŸ‡¨πŸ‡­ for funding our part of this project, enabling @phaips.vd.st to work with us and @mariahondele.bsky.social at the @biozentrum.unibas.ch @unibas.ch. And big high-fiveπŸ™Œ to our YorkπŸ‡¬πŸ‡§ collaborators, led by Gaurav, @james-r-barrett.bsky.social & @mackinderlab.bsky.social

31.01.2026 20:04 πŸ‘ 9 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Here it is @jimhurley.bsky.social. Happy to have some feedback! 😁

bsky.app/profile/jame... πŸ§ͺ

31.01.2026 19:31 πŸ‘ 5 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Resurrected nitrogenases recapitulate canonical N-isotope biosignatures over two billion years - Nature Communications The study shows that nitrogenase enzymes have maintained stable isotope signatures over billions of years, revealing how ancient microbes shaped Earth’s nitrogen cycle and offering a new experimental ...

Our new paper, out today! We resurrected ancient nitrogenases first used by life on Earth 3 billion years ago. We combined synthetic biology and geology & validated their chemical #biosignature in rocks that helps reveal ancient life on Earth!(and beyond!)

Link: www.nature.com/articles/s41...

30.01.2026 21:12 πŸ‘ 66 πŸ” 23 πŸ’¬ 2 πŸ“Œ 3

Super interesting! Congrats, and thanks for sharing :)

30.01.2026 23:07 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Check this new study on carbon concentration mechanisms!

See how the pyrenoid changes by modifying Rubisco linkers in our favorite alga, Chlamy πŸ’š!

My desk mate @phaips.vd.st spent a lot of time collecting & carefully analyzing these beautiful tomograms πŸ”¬.

Congrats to all the authors!

30.01.2026 19:40 πŸ‘ 15 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

That is a really beautiful poster!🀩 πŸ§ͺ

Inside the Pyrenoid: How Multivalency Shapes Rubisco Organization and CO2 Fixation
www.biorxiv.org/content/10.6...

30.01.2026 16:27 πŸ‘ 12 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

You like #LLPS? #TeamTomo? #Rubisco? Check out our latest preprint!

What a great collaboration this has been!

30.01.2026 15:38 πŸ‘ 30 πŸ” 11 πŸ’¬ 0 πŸ“Œ 0

Check out this cool thread on the latest preprint by Gaurav Kumar, @james-r-barrett.bsky.social, @phaips.vd.st from our lab and colleagues, dissecting the physics of Rubisco condensates!

You're in for some stunning #cryoET of the pyrenoid - in Chlamy, of course πŸ˜‰

Congrats to all involved!

30.01.2026 15:54 πŸ‘ 18 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

Excited to share this detailed biophysical study of #PhaseSeparation in the Pyrenoid, an algal microcompartment that fixes a third of the Earth's #CO2 🌏. We combine methods across scales, in vitro πŸ§ͺ and in vivo 🦠

Thanks for the very fun collaboration! πŸ€—
#PlantScience 🌾 #TeamTomo πŸ”¬ #LivingPhysics 🧬🧢

30.01.2026 15:50 πŸ‘ 64 πŸ” 19 πŸ’¬ 1 πŸ“Œ 1
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How do diatom cells maintain a constant supply of carbon for photosynthesis? Our microelectrode measurements of the phycosphere around individual diatom cells show that diatoms can rapidly switch between distinct carbon acquisition pathways. @thembauk.bsky.social www.science.org/doi/10.1126/...

14.01.2026 09:49 πŸ‘ 24 πŸ” 10 πŸ’¬ 1 πŸ“Œ 0

#TeamTomo visualizes amazing (green πŸ’šβ™»οΈ) proteasome crystals in yeast. This project was a long time coming -- I remember talking to Cordula about it back when I was a postdoc in Martinsried. Some really cool and surprising findings here. Nice to see it out, and congrats to all the authors! πŸ§ͺ πŸ”¬

30.01.2026 10:34 πŸ‘ 21 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

SHAPES being the key word, amirite @nanigrotjahn.bsky.social
github.com/GrotjahnLab/...

Should be an interesting #TeamTomo talk. Check it out! πŸ§ͺ πŸ”¬

23.01.2026 12:45 πŸ‘ 19 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

Fair enough.... but actually, archaea are the master extremophiles, and many bacteria have more complex internal architecture than we used to think. It was their equal collaboration and subsequent specialization that made Eukaryotes what they are.

22.01.2026 15:56 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Well, archaea didn't do it alone -- it was an equal partnership with alpha-proteobacteria. Hard to expand into a newly oxic world (2 BYA) without a mitochondrion that can use oxygen as a terminal electron acceptor. πŸ§ͺ

20.01.2026 21:25 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Go #TeamTomo! πŸ§ͺ @wilflinglab.bsky.social & @nanigrotjahn.bsky.social are on a roll! Beautiful in-cell visualization of lysosome rupture 🎈πŸ’₯

20.01.2026 20:36 πŸ‘ 44 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0