Podcast episode: www.youtube.com/watch?v=Ss8H...
12.02.2026 18:01
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Lab tour and takeaways: www.youtube.com/watch?v=nS2o...
We visited Plasmidsaurus and had tons of interesting takeaways, so we went back to record a whole podcast episode with them and film a lab tour for our YouTube channel. Here are both:
Just published an interactive article about a magical algorithm known as the Burrows-Wheeler Transform, which powers sequence alignment tools like bowtie and bwa: sandbox.bio/concepts/bwt
It's also notoriously unintuitive so I'm hoping this article helps you build that intuition.
There's now a race to apply AI to every imaginable field of biology. The problem is: unless you understand the biology really well, it's easy to think you've solved the problem when you haven't even come close.
youtu.be/o097zC7CM5I
We always tell people to create a portfolio to showcase their work, so today we're releasing a template to get you started: github.com/omgenomics/p...
It's made for scientists & engineers who want a living resume that showcases projects, work timeline, and blog posts that demonstrate your expertise
We sent out a calendar invite to everyone who signed up, so check your spam filters!
We just released a new video on how to get more out of those βletβs chatβ conversations when job hunting, based partly on my past experiences being on the receiving end of requests for advice and job referrals:
youtu.be/bpQaIvqqkKw
π§¬π₯οΈ We are hosting free bioinformatics office hours on Feb 19th at 10am-noon PST. Bring your bioinformatics career or technical questions, and @robert.bio and I will try to answer them.
Sign up here: tally.so/r/mOb6dM
Please share especially with students and early career scientists!
Friends are looking for jobs. Collaborators are dropping off papers. Funds are being pulled away. But letβs just pretend everything is normal.
π New RNA-Seq tutorial! Learn to run differential expression analysis with DESeq2, and create your own bioinformatics projects using public data and the Expression Atlas 𧬠π₯οΈ
youtu.be/NGbZmlGLG5w
Before
After
Code (after adjustment)
I almost missed the part where it's not just text size but also the pixel circumference of the track that determines how much space the text needs. This is before and after adding a fix to take circumference into account.
And here's that spirograph case again now that I added some guardrails, namely restricting max total space <= 2Ο. There is a beauty to radial geometry that gets me every time π
I got the heuristics just right so the pins slide over just enough as text gets bigger.
Ooh fun, it's making an interesting pattern when there are too many data points. I think it's because the little pins wrap around so far that they connect to the other side of the circle. It's pretty. Reminds me of the spirograph toy from when I was a kid.
Thanks to the Circa user who requested this for giving me a good excuse to code today :)
I'm working on a little feature for Circa. It's been over a month since I really coded with all the other startup things like marketing and "strategic thinking" taking up my brain space, so it's really nice just to sit down and code a little algorithm and some SVG paths for overlap-avoiding text.
I made a little swiss army knife tool for quickly inspecting FASTA/FASTQ sequences, including GC content, codon analysis, reverse complement, and file format conversions: π₯οΈ π§¬
42basepairs.com/tools/sequen...
𧬠π₯οΈ This was a fun one to make: We reviewed 10 CVs sent in by our audience, and here are the 7 common mistakes we kept seeing: youtu.be/qXPJpnrfX_4
We just released 8 new data wrangling tutorials for biologists! sandbox.bio/community/da... π» π§¬
Check out this 1-minute mini-tutorial for Circa 2.0
youtu.be/e_zjPY2vpaM
From a paper about the Genbank database: "the database is available to any user in several forms: it is distributed on magnetic tape, on floppy diskettes and on-line" :)
If you think bioinformatics is hard today, you should have seen it in 1985 π¬ 𧬠π₯οΈ
Investigating structural variants? I just released a tutorial video showing how I do this quickly and intuitively using my tools Ribbon and SplitThreader:
youtu.be/TP-H9epbsTM
#bioinformatics
Here are 3 ways I made money on the side with bioinformatics during my PhD:
www.youtube.com/watch?v=Q64t...
The backstory behind the FASTA bioinformatics format
π§¬π₯οΈ
youtu.be/7LA0IKsVloU?... via @YouTube
Wait, why arenβt folks using their own domains. Am I missing something?
Now I am! Thanks for the push :)
Huh yes! With fractional teaspoon and tablespoon measures marked all on the same pipetteβ¦
