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Christian Brueffer

@brueffer.io

Consultant in #bioinformatics and #cancer applications @insilico.consulting (all things #genomics, #liquidbiopsy, and #workflows) โ€ข ๐Ÿ‡ธ๐Ÿ‡ช ๐Ÿ‡ฉ๐Ÿ‡ช โ€ข ๐Ÿงฌ๐Ÿ–ฅ๏ธ โ€ข https://brueffer.io ORCiD: 0000-0002-3826-0989

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08.09.2023
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Latest posts by Christian Brueffer @brueffer.io

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Postdocs at Center for Gene Expression in Department of Cellular and Molecular Medicine - Copenhagen, Hovedstaden (DK) job with University of Copenhagen | 12849488 We are looking for 2 or more highly motivated postdocs interested in ribosome biology, 3D chromatin organisation, or regulation of protein turnove...

We are looking for a Postdoc at the Center for Gene Expression in Copenhagen. Deadline for applications is the 11th of January. If you are interested in 3D chromatin, SMC complexes, and super-resolution microscopy, join us. www.nature.com/naturecareer...

02.01.2026 08:12 ๐Ÿ‘ 21 ๐Ÿ” 25 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 2

There's an opening in our CompBio group at #PacBio. Apply below if you're interested in method / tool development for long-read sequencing applications! #Bioinformatics

pacbio.wd12.myworkdayjobs.com/PacBio-/job/...

12.12.2025 18:40 ๐Ÿ‘ 13 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Senior Postdoctoral Fellow Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanityโ€™s greatest challenge...

Hiring Senior Computational Postdoc to lead large-scale scRNAseq analysis for Project JAGUAR, one of the worldโ€™s most comprehensive single-cell immune resources from Latin American ancestries. If big data, global partnerships, human diversity and immune regulation excite you, apply! bit.ly/3XyFWrW

04.12.2025 09:06 ๐Ÿ‘ 7 ๐Ÿ” 8 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Intro to Bedder โ€“ The Quinlan Lab

We are thrilled to announce the first official release (v0.1.8) of #๐—ฏ๐—ฒ๐—ฑ๐—ฑ๐—ฒ๐—ฟ, the successor to one of our flagship tool, #๐—ฏ๐—ฒ๐—ฑ๐˜๐—ผ๐—ผ๐—น๐˜€! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen.

1/n

02.12.2025 02:28 ๐Ÿ‘ 298 ๐Ÿ” 152 ๐Ÿ’ฌ 5 ๐Ÿ“Œ 11
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Data Scientist in Sutton | The Institute of Cancer Research View details and apply for this Data Scientist vacancy in Sutton. Salary : Salary range ยฃ39,805 to ยฃ53,500 (Dependent on experience ) Reporting to: Professor Trevor Gra...

Calling cancer data scientists! ๐Ÿ“Š ๐Ÿ’ฝ ๐Ÿงฎ
We have a number of open positions in our core facility @icr.ac.uk These are bioinformatician staff scientist like roles to work on exciting single cell, spatial & other genomics data from across our Institute. A PhD is required. jobs.icr.ac.uk/vacancies/13...

13.11.2025 14:59 ๐Ÿ‘ 13 ๐Ÿ” 13 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Opportunity!
Anybody knows of young marine ecologists (within 7 years from earned PhD) that would like to come to Gothenburg, Sweden, for a nationally funded Assistant Professorship? It is highly competitive but well funded. (1) of (3)

10.11.2025 09:32 ๐Ÿ‘ 24 ๐Ÿ” 46 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 0
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Conda in the Packaging Spectrum: From pip to Docker to Nix | conda.org Part 2 of the 'Conda Is Not PyPI' series, placing conda among pip, Docker, and Nix and explaining its middle-path design.

Conda in the Packaging Spectrum: From pip to Docker to Nix

If conda is a distribution, where does it fit alongside pip, Docker, and Nix? Part 2 of the 3-part series! ๐Ÿš€

#conda #packaging #python

conda.org/blog/conda-p...

04.11.2025 14:38 ๐Ÿ‘ 13 ๐Ÿ” 7 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Stellenangebote: Universitรคt Hohenheim Aktuelle Stellenangebote der Universitรคt Hohenheim.

The Cluster of Excellence @greenrobust.de is hiring:

- Computer Scientist/Research data manager: shorturl.at/xSvvO
- Data steward: shorturl.at/l6NCv
- Scientific coordinator 'Plant Perturbation Atlas': shorturl.at/vBU6x

Deadline: Friday, 7 November 2025

RT are welcome

#plantjobs #plantscijobs

07.10.2025 09:59 ๐Ÿ‘ 18 ๐Ÿ” 26 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Heads up: ignore samtools dot org, similarly minimap2 dot com and likely others. It's owned by a known phishing site and while the binaries they offer look valid currently (but note they may be serving us different binaries to others), that could change.

Ie: it's not us (Samtools team)! Be warned

15.09.2025 08:40 ๐Ÿ‘ 146 ๐Ÿ” 127 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 5
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Postdoctoral position - Uppsala University Postdoctoral position, Department of Immunology, Genetics and Pathology, Uppsala University

A postdoc position in genomics available at our infrastructure in Uppsala, Sweden! An interesting R&D role a bit outside the traditional academic environment, great colleagues, work at the forefront of (long-read) sequencing.

www.uu.se/en/about-uu/...

19.08.2025 13:21 ๐Ÿ‘ 37 ๐Ÿ” 38 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1

Done!

20.08.2025 18:40 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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๐Ÿ“ฃ๐Ÿ“ฃ Cool job alert! The @bakerresearchau.bsky.social is recruiting up to 2 new PIs in Biomedical Data Science ๐Ÿ‘‰ www.seek.com.au/job/85989791...

Youโ€™d join an awesome institute in an incredible city (Melbourne, Australia) as well as partnerships like with @cam.ac.ukโ€ฆ youโ€™ll also get to work with me ๐Ÿ˜

25.07.2025 07:24 ๐Ÿ‘ 19 ๐Ÿ” 18 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
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Tenure-Track Assistant Professor / Associate Professor in Bioinformatics at Aarhus University, Denmark - Vacancy at Aarhus University Vacancy at Department of Molecular Biology and Genetics - BiRC - Bioinformatics Research Center, Aarhus University

๐Ÿ“ฃ ๐Ÿฅณ ๐Ÿง‘โ€๐Ÿ’ป Our department is hiring:

Tenure-Track Assistant Professor / Associate Professor in Bioinformatics at Aarhus University, Denmark

Deadline June 1st

Thanks for sharing!

mbg.au.dk/en/news-and-...

16.05.2025 12:35 ๐Ÿ‘ 70 ๐Ÿ” 90 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Short RNA-seq read alignment with minimap2

Minimap2-2.29 released with the support of short RNA-seq read alignment. More explanation and results here: lh3.github.io/2025/04/18/s...

18.04.2025 21:53 ๐Ÿ‘ 29 ๐Ÿ” 7 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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GitHub - ACEnglish/truvari: Structural variant toolkit for VCFs Structural variant toolkit for VCFs. Contribute to ACEnglish/truvari development by creating an account on GitHub.

๐Ÿš€ Truvari v5.0 is here! ๐ŸŽ‰
Whatโ€™s new?
๐Ÿ”น Enhanced symbolic variant support for <DEL>, <DUP>, <INV>
๐Ÿ”น Robust BND comparison for cross-representation SV matching
๐Ÿ”น Improved SV sequence similarity & HUGE SV support
๐Ÿ”น Cleaner UI & Revamped API

๐Ÿ‘‰ More: github.com/ACEnglish/tr...
#Genomics #Bioinformatics

10.01.2025 13:43 ๐Ÿ‘ 6 ๐Ÿ” 5 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

#ICYMI our deep dive into ALK1 biology, at the intersection between angiogenesis and immunology with clear implication for the targeting of immunomodulatory cues & cancer therapy!

13.03.2025 15:51 ๐Ÿ‘ 1 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Thirty Years of BRCA1: Mechanistic Insights and Their Impact on Mutation Carriers Abstract. Thirty years ago, the cloning of the first breast cancer susceptibility gene, BRCA1, marked a milestone in our understanding of hereditary breast and ovarian cancers. This discovery initiate...

BRCA1 turned 30 ๐ŸŽ‰
To celebrate, Jos Jonkers and I explored three decades of BRCA1 research - what weโ€™ve learned about its biology, its role in tumorigenesis and future directions to improve the life of BRCA1 mutation carriers.
Now out in Cancer Discovery โฌ‡๏ธ: aacrjournals.org/cancerdiscov...

03.03.2025 09:26 ๐Ÿ‘ 62 ๐Ÿ” 26 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 2
Index of /ReferenceSamples/giab/data_somatic/HG008/Liss_lab/analysis/NIST_HG008-T_somatic-stvar_DraftBenchmark_V0.1-20241219

Our first curated draft somatic structural variant benchmark for the new GIAB PDAC tumor cell line HG008-T is at ftp-trace.ncbi.nlm.nih.gov/ReferenceSam..., based on extensive short+long read sequencing data described in doi.org/10.1101/2024.... Feedback to improve future versions is very welcome!

20.12.2024 18:04 ๐Ÿ‘ 15 ๐Ÿ” 8 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Regular abstracts from #SABCS24 are out!

3407 pages of new breast cancer discoveries.

Find them here: sabcs.org/Portals/0/Do...

25.11.2024 23:41 ๐Ÿ‘ 62 ๐Ÿ” 15 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Added!

24.11.2024 13:59 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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two women are standing next to each other and one of them is saying i 'm so glad that you are here ALT: two women are standing next to each other and one of them is saying i 'm so glad that you are here

WOOT!
Just in time for #SABCS24 looks like @sabcs.bsky.social is officially on BlueSky!
cc: @maryamlustberg.bsky.social @drsgraff.bsky.social @stage4kelly.bsky.social @amjohnston.bsky.social @amybeumer.bsky.social @raalbany.bsky.social @hoperugo.bsky.social

21.11.2024 18:42 ๐Ÿ‘ 18 ๐Ÿ” 5 ๐Ÿ’ฌ 7 ๐Ÿ“Œ 2

Added!

20.11.2024 21:32 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Done!

20.11.2024 20:12 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Done! Sorry for the delay, notifications have been mad the last couple of days, so this one slipped through.

19.11.2024 06:41 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Done and welcome!

19.11.2024 06:31 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

I dont care for either but my sambo has needs ;-)

17.11.2024 09:21 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Vegemite too by any chance?

17.11.2024 09:17 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Happy to join the bioinformatics + genomics starter. Thanks for the work!

16.11.2024 16:50 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Done!

16.11.2024 16:26 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Dear Colleagues,
For all of you in BlueSky, Greetings, We are Now Here!!
We invite you to Join & Follow OncoAlert at @oncoalert.bsky.social
Thank you for your support!

16.11.2024 13:31 ๐Ÿ‘ 15 ๐Ÿ” 7 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0