Mauricio Contreras's Avatar

Mauricio Contreras

@mpcontreras

Junior Group Leader at @zmbp-tuebingen.bsky.social NLR and effector biology πŸ‡¦πŸ‡·

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26.10.2023
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Latest posts by Mauricio Contreras @mpcontreras

$1B per day is about $42 million per hour. About 30 min worth of that spending can fund my lab for my ENTIRE career (~20 3-year NSFs or ~10 5-year R01s). Please wrap your head around that.

05.03.2026 03:00 πŸ‘ 52 πŸ” 18 πŸ’¬ 1 πŸ“Œ 0
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We are inviting applications for a joint appointment:

Director at the Leibniz Institute of Plant Biochemistry

Full Professor (W3) at MLU

Apply by April, 24 via: berufungsportal.uni-halle.de

Join us in advancing innovative research at the interface of chemistry and bioactive natural products.

04.03.2026 14:36 πŸ‘ 16 πŸ” 21 πŸ’¬ 0 πŸ“Œ 0

Another great article by @mastroianni.bsky.social on the current #SciencePublishing system.

Don't publish with for-profit publishers like Elsevier, Springer Nature, et al. It's really simple. There are so many cool #PlantScience society journals. #SciPub

See also: bsky.app/profile/soms...

04.03.2026 07:20 πŸ‘ 15 πŸ” 5 πŸ’¬ 2 πŸ“Œ 3
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Kick-off meeting of our GreenRobust cluster of excellence last week. Exciting times ahead for plant sciences by bringing together an extraordinary bunch of enthusiastic scientists and human beings!

04.03.2026 08:12 πŸ‘ 28 πŸ” 13 πŸ’¬ 1 πŸ“Œ 1
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The one science reform we can all agree on, but we're too cowardly to do OR: the long overdue forest fire

Wonderful (and fun!) read from @mastroianni.bsky.social which finishes with a clear answer on how to solve the collective action problem of dismantling scientific publishing

03.03.2026 18:40 πŸ‘ 12 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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Attending @micronorwich Annual Conference? ReSay Podcast organising micro-quiz / mega-impact. You can register here buff.ly/uP2iWNI

There are prizes on offer, Β£2 entry fee will go toward
@getgenome.bsky.social supporting researchers across global south. Donations are matched too!

03.03.2026 22:53 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1
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Paralog interference contributes to the preservation of genetic redundancy Duplicated self-interacting proteins can interact and interfere with each other’s function. Cisneros, Mattenberger, et al. show that selection against interfering loss-of-function alleles extends the ...

New paper alert: Paralog interference contributes to the preservation of genetic redundancy www.cell.com/current-biol...

28.02.2026 02:00 πŸ‘ 45 πŸ” 28 πŸ’¬ 0 πŸ“Œ 0

Cell death is a fundamental mechanism of antiviral immunity across diverse organisms, including bacteria. As my final PhD project with @jbdsf.bsky.social, I was curious whether cell death is required for successful immunity with the ancient cGAS pathway known as β€˜CBASS.’

Spoiler – the answer is no!

26.02.2026 16:25 πŸ‘ 36 πŸ” 14 πŸ’¬ 2 πŸ“Œ 2
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RNA splicing generates a functionally specialized Rep protein isoform in geminiviruses β€” enabling timely control of the viral cycle. Strikingly, similar strategies might have evolved in DNA viruses infecting different kingdoms: www.biorxiv.org/content/10.6... Spearheaded by @delphinem-p.bsky.social!

20.02.2026 09:31 πŸ‘ 51 πŸ” 34 πŸ’¬ 0 πŸ“Œ 1
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AI Research Scientist | Protein-Protein Interactions Resurrect Bio

Following the successful completion of the Series A funding round, our plant disease resistance start-up Resurrect Bio @resurrectbio.bsky.social is hiring for its London lab:

(1/2) AI Research Scientist | Protein-Protein Interactions

jobs.recruit.charliehr.com/resurrect/ai...

18.02.2026 15:15 πŸ‘ 8 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
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Structural biology is in an era of dynamics & assemblies but turning raw experimental data into atomic models at scale remains challenging. @minhuanli.bsky.social and I present ROCKETπŸš€: an AlphaFold augmentation that integrates crystallographic and cryoEM/ET data with room for more! 1/14.

24.02.2025 12:22 πŸ‘ 144 πŸ” 63 πŸ’¬ 6 πŸ“Œ 5
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We’re hiring!

Postdoctoral Researcher / Research Assistant @KamounLab

β€œBiology and Applications of Plant Immune Receptors” www.tsl.ac.uk/working-at-t...

13.02.2026 14:18 πŸ‘ 37 πŸ” 43 πŸ’¬ 0 πŸ“Œ 1

A really cool #PlantImmunity paper showing that the ubiquitin-binding protein RH3 recruits PTI & ETI receptors into one large complex via ubiquitin chains, linking these pathways.

Also goes well with this paper showing a link between BIK1 & NLRs via phosphorylation: www.nature.com/articles/s41...

12.02.2026 09:49 πŸ‘ 20 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

Ubiquitin recognition integrates plant immune signaling by cell-surface and intracellular receptors https://www.biorxiv.org/content/10.64898/2026.02.06.703835v1

07.02.2026 11:01 πŸ‘ 14 πŸ” 7 πŸ’¬ 0 πŸ“Œ 2
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Scientific coordinator at the GreenRobust location Heidelberg (f/m/d) - UniversitΓ€t Heidelberg UniversitΓ€t Heidelberg looks for Scientific coordinator at the GreenRobust location Heidelberg (f/m/d) in Heidelberg - apply now!

Our cluster of Excellence GreenRobust is looking for a scientific coordinator located at Heidelberg University. Please spread the word!
www.academics.com/jobs/scienti...

06.02.2026 09:30 πŸ‘ 9 πŸ” 14 πŸ’¬ 0 πŸ“Œ 0
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Postdoctoral position in biology (m/f/d) (2/2026) Leibniz Institute of Plant Biochemistry (Halle) offers a Postdoctoral position in Biology

Please share! We are looking for a postdoctoral scientist (2 years, extension possible) starting from 01/05/2026 at
@ipbhalle.bsky.social! The project focuses on plant immune receptor biochemistry and structural biology.
Deadline 09/03/2026.

Apply at: ipb-halle.mhm.jobs/11-postdocto...

05.02.2026 09:07 πŸ‘ 47 πŸ” 56 πŸ’¬ 0 πŸ“Œ 1
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Please share!
PhD position (4 years) available in my group @zmbp-tuebingen.bsky.social. We look for candidates with solid aptitude in computer science to cross disciplines and use cutting edge imaging to understand host infection by destructive plant pathogens.
uni-tuebingen.de/universitaet...

30.01.2026 15:04 πŸ‘ 48 πŸ” 69 πŸ’¬ 2 πŸ“Œ 1
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Please share!
My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th!
uni-tuebingen.de/universitaet...

30.01.2026 13:56 πŸ‘ 83 πŸ” 118 πŸ’¬ 0 πŸ“Œ 3

πŸ“’ Job alert! @delaconcepcionjc.bsky.social, junior group leader at #ZMBP, has 2 open positions (PhD and postdoc) to investigate appressoria formation in plant pathogenic #fungi using #cryoEM and #cryoET
#EmmyNoether #MPMI #plantscijob
More info πŸ‘‡

03.02.2026 09:14 πŸ‘ 11 πŸ” 9 πŸ’¬ 1 πŸ“Œ 0

Exciting PhD positions on plant immunity and engineering plant disease resistance with an excellent supervisor @jiorgoskourelis.bsky.social. Strongly recommend.πŸ‘‡

23.01.2026 09:46 πŸ‘ 5 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0
PhD Opportunities | Faculty of Natural Sciences | Imperial College London

πŸ“’ 2 PhD Positions Available in Plant Immune Receptor Bioengineering at Imperial College London
🌱 Start: Oct 2026
πŸ“… Deadline: 10 Feb 2026
πŸ‡¬πŸ‡§ UK/settled status only
πŸ’° Fully funded (48 months)
ℹ️ Info: shorturl.at/po61I
#PlantImmunity #PlantPathology #SyntheticBiology
πŸ™ Share with interested candidates!

23.01.2026 09:32 πŸ‘ 21 πŸ” 31 πŸ’¬ 0 πŸ“Œ 1
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Activities - GreenTE Activities Webinars ”MechanoBioTalks – Mechanics, Materials and Living Matter” is a webinar series supported by the GreenTE consortium and organized […]

A new webinar series is born - ''MechanoBioTalks - Mechanics, Materials and Living Matter", to bring together and inspire researchers interested in biomechanics, biophysics and biology across different kingdoms of life. Join us!

For info and registration visit green-te.nl/activities/

22.01.2026 08:18 πŸ‘ 12 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0
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AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications AI-powered pipeline converts antibodies into functional intrabodies, enabling live-cell imaging of peptides and histone marks.

Happy New Year all. I know it's been a draining and difficult year for science in general, but wanted to share some good news: our intrabody paper has now been published in Science Advances with lots of additional data.
www.science.org/doi/10.1126/...

19.01.2026 17:43 πŸ‘ 41 πŸ” 19 πŸ’¬ 3 πŸ“Œ 0
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Structome-AlignViewer: On Confidence Assessment in Structure-Aware Alignments Abstract. Protein structure-based comparison provides a framework for uncovering deep evolutionary relationships that can escape conventional sequence-base

An interesting way to look at encoded structural characters to build alignments and trees downstream. This takes structural phylogenetics one step further in the post-AlphaFold era.

#Evolution #Science #StrPhy

On Confidence Assessment in Structure-Aware Alignments

doi.org/10.1093/gbe/...

14.01.2026 11:07 πŸ‘ 18 πŸ” 10 πŸ’¬ 0 πŸ“Œ 0
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A multi-plant transcriptomic atlas reveals conserved and lineage specific defense architectures in response to Botrytis cinerea Generalist pathogens pose a challenge to plant immunity by infecting diverse hosts while harboring extensive intraspecific genetic variation. Whether evolutionary distant plant lineages rely on a shar...

Ever wondered if diverse plant species respond similarly when infected by the same exact pathogen? Infect different asterids and rosids with the same Botrytis genotypes and teh short answer, quite differently.
www.biorxiv.org/content/10.6...

@annajomu.bsky.social @ccaseys.bsky.social

(1/3)

15.01.2026 22:52 πŸ‘ 34 πŸ” 24 πŸ’¬ 1 πŸ“Œ 0

ECRs in plant–microbe interactions:

Join us in Norwich for an intensive, interactive 1.5-week Summer Conference at TSL (20–31 July). Lots of opportunities for networking and deep discussions.

(We also plan to offer hands-on practical sessions using our technologies πŸ”¬πŸ§¬)

15.01.2026 09:03 πŸ‘ 29 πŸ” 31 πŸ’¬ 0 πŸ“Œ 0

@ismpmi.bsky.social members please check your emails for ballots to vote on bylaw changes. didnt get a ballot? contact Jean Greenberg

14.01.2026 16:55 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 2
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Excited to share this commentary on the work by Isaksson et al, now out in @mpmijournal.bsky.social, where they find that structural similarity underlies both multimerization and NLR recognition of a powdery mildew effector family
doi.org/10.1094/MPMI...

Original paper πŸ‘‰ doi.org/10.1094/MPMI...

12.01.2026 17:47 πŸ‘ 6 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Towards a quantitative view of NLR evolution in genome space -- check out where we think the field of #NLR #evolution research is heading in this review led by Luzie Wingen and AurΓ©lien Tellier.
ecoevorxiv.org/repository/v...
#plantscience

06.01.2026 09:05 πŸ‘ 26 πŸ” 18 πŸ’¬ 0 πŸ“Œ 0
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Postdoctoral Researcher (Faulkner Group) | John Innes Centre An exciting opportunity has arisen for a Postdoctoral Researcher to join the Faulkner Group at the John Innes Centre, working on cutting-edge science in the field of Cell & Developmental Biology.

We're looking for a postdoc to join us in trying to map the routes by which different signals travel through plants and identify what information they carry. LinkπŸ‘‡or get in touch! @johninnescentre.bsky.social

#PlantSciJobs

www.jic.ac.uk/vacancies/po...

22.12.2025 13:30 πŸ‘ 36 πŸ” 33 πŸ’¬ 0 πŸ“Œ 1