Stimulating Brains

For a discussion of why our conclusions may differ from those of van den Heuvel et al., please see our preprint:
www.biorxiv.org/content/10.6...

A recent @natneuro.nature.com paper analyzed lesion network mapping and raised concerns about the validity of the method.
See below 👇 for our response.

www.biorxiv.org/content/10.6...

The deep brain stimulation response network in Parkinson’s disease operates in the high beta band Bahners et al. identify a brain network linked to optimal therapeutic outcomes in patients with Parkinson’s disease receiving deep brain stimulation. This

New @netstim.org publication alert: @bahnebahners.bsky.social in BRAIN out now:

academic.oup.com/brain/advanc...

A 🧵:

"You see what you look for, and you look for what you know."

We are proud to release FOCUS: a 100 μm deformable human subcortical atlas precisely registered to MNI space.

www.biorxiv.org/content/10.6...

✨ Be there or be square! ✨

In our upcoming Stimulating Brains session (Feb 26, noon ET / 6 pm CET), let’s dive into the brain networks driving chronic pain and how adaptive DBS is changing treatment!

🎤 Feat. Valentina Lind & Prasad Shirvalkar

🔗 Get your Zoom link here: talks.stimulatingbrains.org

Kölle Alaaf from the @netstim.org!

🧠 Deep brain stimulation for Parkinson’s disease achieves its best results when a precisely defined brain network operating in the high beta frequency range is targeted. This was shown by a team @andreashorn.org @bahnebahners.bsky.social in both space and time for the first time.👇
uni.koeln/5LYV7

🧠 Die Tiefe Hirnstimulation bei Parkinson zeigt ihre bestmögliche Wirkung, wenn ein präzises Gehirnnetzwerk im Beta-Frequenzbereich (20–35 Hz) stimuliert wird – das zeigt ein Team um @andreashorn.org @bahnebahners.bsky.social jetzt erstmals gleichzeitig räumlich und zeitlich👇
youtu.be/ZrREFuDI-as

It was a great joy to talk to Ludvic Zrinzo about DBS, lesioning and how it all may work: stimulatingbrains.org/74-ludwig-zr...

Thanks to Niels Pacheco for producing the episode!

🧠⚡ New year, fresh StimBrains talks!

Join us when we explore the brain networks driving schizophrenia & how we can treat them via DBS.

January session (Thurs, Jan 29, noon ET / 6pm CET)
feat. the amazing @andrewpines.bsky.social & Nicola Cascella

✨ Get Zoom link here: talks.stimulatingbrains.org

What is the status of DBS for epilepsy?
Find out in our new review/metaanalysis spearheaded by @laurenahart.bsky.social & Garance Meyer in JNNP: pubmed.ncbi.nlm.nih.gov/40666371/

A 🧵 — please RT for reach! 🙏

See you in Geneva! We have such an incredible line up of speakers this year!
#optoDBS2026 – registration now open at www.optodbs.ch

As last time, we are expanding scope way beyond just DBS and optogenetics – for instance including TMS and LIFU applications this year!

🎄🧠 Ho ho ho! Let’s close out the year with fresh insights into the brain networks behind creativity — and what happens when they go awry.

Our December session (Thurs, Dec 18, noon ET / 6pm CET) will feat. @isaiahneuro.bsky.social & Ben Shofty.

✨ Get Zoom link here: mgb-org.zoom.us/webinar/regi...

Loading...the Oct edition of the Talk series!
When --> Thurs, Oct 30th, 2025/ 12:00 PM EST / 6:30 PM CET
Ft. Alessia Cavallo & Svjetlana Miocinovic who will deep dive into all things electrophysiology - from state dependent effects to optimization!
Register here: mgb-org.zoom.us/webinar/regi...

🧠✨Join us Thurs, Sept 25 — 12 PM EST / 6 PM CET to explore how fronto-basal ganglia circuits drive goal-directed behavior in Parkinson’s & how adaptive DBS moves from pathophysiology to clinical care, with @colinwhoy.bsky.social & Andrea Kühn!
👉 Register here: mgb-org.zoom.us/webinar/regi...

Next steps ahead for DBS! 👇👇

Konstantin Butenko compares four methods for mapping structural network activations in deep brain stimulation—two simple, two complex; some deterministic, some probabilistic—into @lead-dbs.org for direct use in the Fiber Filtering Explorer. See the methods paper below 👇👇

How should we best model recruitment of axons by deep brain stimulation?
Various concepts have been introduced and Konstantin Butenko just introduced a few more in a new publication at Brain Communications:

academic.oup.com/braincomms/a...

New Institute paper out 👇👇

The talk series is back after a summer break! 🌞 Join us Aug 28 at noon ET / 6 PM CET for a fascinating session with the academic power duo @dorahermes.bsky.social & Kai Miller! 🧠✨ They’ll explore how single-pulse signals reveal biomarkers and map brain connectivity. Don’t miss it!

We had a wonderful time talking to @rolstonjohn.bsky.social, the Director of Epilepsy Surgery at Brigham & Women's Hospital. We talk about RNS for epilepsy, DBS for coma, traveling waves in the brain, stem cell therapy, closed loop DBS & more! Tune in 👇

stimulatingbrains.org/72-john-rols...

🧠 ⚡️ Preprint alert ⚡️ 🧠

I️n the most comprehensive review of DBS in epilepsy, with 124 studies, 1,210 patients, and 20 anatomical targets we map where stimulation works best and why.

Deep Brain Stimulation for Epilepsy: Optimal Targeting and Clinical Outcomes
www.researchgate.net/publication/...

Massive, Herculanean work by @laurenahart.bsky.social and Garance Meyer to compile and integrate findings from DBS for epilepsy (20 targets!) including meta-analytical evidence for optimal stimulation sites for the two main targets (ANT & CM). Preprint out now 👇👇

We are actively looking for an administrative position to help lead the newly founded @netstim.org at the University of Cologne – please spread the word and/or let us know if you know somebody that could be interested!

lnkd.in/eEbnXByJ

Excited to be featured as one of the best neuroscience podcasts on millionpodcasts: www.millionpodcasts.com/neuroscience...

@foxmdphd.bsky.social's legendary anticorrelation paper has now been cited over 10.000 times and this was reason for a dedicated PNAS cake. Congratulations again, Mike, for this unbelievable pioneering effort that opened up the then novel field of resting-state fMRI!

@braincircuits.bsky.social

Hard to keep track about all the great things our labmembers have achieved recently:

Happening today! We have two amazing speakers, Nicole Provenza and Martijn Figee who will share their thoughts on engineering for Neuromodulation and circuit based DBS for OCD respectively.

Be sure to tune in on May 29th, 12 noon EST/6:00 PM CET

Register here: partners.zoom.us/webinar/regi...

Are we on the cusp of moving beyond the levodopa challenge test to predict the best candidates and response to DBS in Parkinson's disease? We’ve long relied on the levodopa challenge to decide who’s a good candidate for deep brain stimulation but what if that test is only part of the story?

Is there a shared brain circuit target for tremor that transcends diagnosis and DBS site? New work by @lukasgoede.bsky.social @andreashorn.org @braincircuits.bsky.social says YES