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Kamal

@kamalasaurus.com

Former engineer • Ph.D. student in Biology interested in structural evolution of plant resistance proteins, pathogen effectors, and the generative design of proteins • co-advised by https://bergelsonlab.org and https://huanglab.rbind.io • Art enthusiast

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Latest posts by Kamal @kamalasaurus.com

:)

06.03.2025 16:12 👍 1 🔁 0 💬 0 📌 0

So we’re about halfway through the life of our sun. So maybe 4 eons left? Like the 4 before us.

14.01.2025 01:51 👍 3 🔁 0 💬 0 📌 0
Belome is a 4-eyed, 4-horned, bipedal people eater with a canid shout, a lolling tongue and sabered teeth.  They have red spiral markings in lieu of spots upon a tallow-toned coat.  They are remembered as an original character and final encounter in the Kero Sewers submap of Super Mario RPG:  Legend of the Seven Stars.  They are weak to lightning-element attacks and to their own perpetual hunger.

Belome is a 4-eyed, 4-horned, bipedal people eater with a canid shout, a lolling tongue and sabered teeth. They have red spiral markings in lieu of spots upon a tallow-toned coat. They are remembered as an original character and final encounter in the Kero Sewers submap of Super Mario RPG: Legend of the Seven Stars. They are weak to lightning-element attacks and to their own perpetual hunger.

Looks like Belome from Mario RPG

02.01.2025 16:59 👍 2 🔁 0 💬 0 📌 0

“smolts” :)

31.12.2024 14:37 👍 0 🔁 0 💬 0 📌 0

Even us TAs were caught in the blast wave

30.12.2024 04:07 👍 8 🔁 0 💬 0 📌 0

This is a very elegant explanation—thank you!

09.12.2024 22:54 👍 1 🔁 0 💬 0 📌 0

Will do ✨

06.12.2024 01:08 👍 1 🔁 0 💬 0 📌 0

This is super cool! Are you using RFDiffusion/ESM as a starting point? 🤔 and then adj and ss are precomputed with other tools.. so they need to be in .pt format to be ingested by the model? I haven’t tweaked model inputs at that level before—I’ll give it a think and ask around~

05.12.2024 02:46 👍 2 🔁 0 💬 2 📌 0

I recently learned these are carnivorous (they eat slugs and bugs). Does anyone know how to raise carnivorous larvae? For repopulation purposes… they’re going extinct here.

28.11.2024 15:22 👍 1 🔁 0 💬 0 📌 0

Is it possible to insert adversarial content for tampered browsers and headless traffic? Like replace the text with random letters so it’s untrainable, or render nothing. Also if the user doesn’t consent. I guess you would have to mask for the firehose as well? That could make it harder to federate?

27.11.2024 10:08 👍 0 🔁 0 💬 0 📌 0

I’d forgotten the name of Polari the other week, and none of my rhymed memory fragments were autocorrecting the right way when I tried looking it up. Thanks for leaving a breadcrumb!

27.11.2024 03:27 👍 2 🔁 0 💬 0 📌 0

26.11.2024 20:53 👍 0 🔁 0 💬 0 📌 0

Super cool! How large of cargo can you put in (say, an entire cas9 + template)?

26.11.2024 17:19 👍 0 🔁 0 💬 1 📌 0

That’s interesting! I struggle with tons of false positives in protein-protein AlphaFold-type simulations—since it seems to clobber its way through the interaction on the assumption it does interact. Maybe ligands have a false negative problem? I don’t have an intuition for it.

26.11.2024 10:30 👍 2 🔁 0 💬 0 📌 0
Slides from a presentation describing a hearsay history of the R tidyverse package.

Slides from a presentation describing a hearsay history of the R tidyverse package.

I just went over an abbreviated version of the history in the Biostats class I TA. Is this accurate? I feel like it’s a bit hearsay from what I could find. I’m looking forward to your authoritative version! To correct what I got wrong :)

26.11.2024 03:48 👍 0 🔁 0 💬 1 📌 0
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I was surprised by @martinsteinegger.bsky.social's recent paper stating 99% of viral proteins to be <1500aa long, since I've never thought about it before. This cropped figure from Yannis Nevers' analysis last year doi.org/10.1186/s130... suggests all domains might similarly have 99% < 1500aa! Cool!

25.11.2024 06:39 👍 4 🔁 0 💬 0 📌 0

I actually wanted to use twitter as a comments engine in the past but couldn’t get the whole conversation to show up with the supported embedding setup—great to see it’s actually possible with 🦋

25.11.2024 00:51 👍 0 🔁 0 💬 0 📌 0

This is super cool! The structural diversity is very exciting ✨

24.11.2024 01:07 👍 1 🔁 0 💬 0 📌 0

If the rest is of interest, I’m the molecular plant-pathogen interaction guy!

23.11.2024 01:48 👍 0 🔁 0 💬 0 📌 0

👋 Thanks for posting! I just applied -- I didn't tailor my research statement to healthcare though, I just loosely described one of my thesis aims. I hope it's sufficient!

22.11.2024 23:48 👍 0 🔁 0 💬 1 📌 0
Post image Post image Post image

Forgive the mediocre resolution -- is this the full text?

22.11.2024 18:17 👍 1 🔁 0 💬 0 📌 0

Is this because any reversible/lossless compression has to fully represent the initial domain to be reversible or does the network learning on it have to learn how to unzip? I guess it would learn some representation of the (un)encoded input regardless 🤔

22.11.2024 12:03 👍 1 🔁 0 💬 1 📌 0
Preview
Terra preta - Wikipedia

I’ve been a terra preta (en.m.wikipedia.org/wiki/Terra_p...) fan myself—dunno if it made it up to the Mayans in the Yucatán!

20.11.2024 04:08 👍 1 🔁 0 💬 0 📌 0

This reddit post is pretty informative: www.reddit.com/r/bioinforma... the part that jumped out was point 2: “ the absence of protein-internal solvent atoms can easily result in collapse or destabilization of the protein's structure” so you need to add water atoms and stuff.

10.10.2024 14:05 👍 1 🔁 0 💬 0 📌 0